Product Information
ADVAIR 100-50 DISKUS is a brand product labeled by GlaxoSmithKline LLC, priced at $2.4861 per EA under NDC 00173069500. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Aug 24, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100; 50 ug/1; ug/1
Manufacturer
GlaxoSmithKline LLCNDC
00173069500
Classification
Brand
Dosage Form
POWDER
Route
RESPIRATORY (INHALATION)
Effective Date
8/19/2026
Active Ingredients
FLUTICASONE PROPIONATE; SALMETEROL XINAFOATEApproval Type
New Drug (NDA)
FDA Application
NDA021077FDA Approved
8/24/2000
TE Code
AB
On Market Since
2/28/2001
Pharmacological Classes
Price Statistics
The NADAC for ADVAIR 100-50 DISKUS has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 29.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.4861 per EA |
|---|---|
| All-time high | $5.0722 (Aug 14, 2019) |
| All-time low | $2.4861 (Aug 19, 2026) |
| 52-week high | $2.4896 |
| 52-week low | $2.4861 |
| Median price | $4.6587 |
| Average price | $4.2405 |
| Largest weekly change | -50.8% (Dec 27, 2023) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 55% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ADVAIR 100-50 DISKUS?
The current National Average Drug Acquisition Cost (NADAC) for ADVAIR 100-50 DISKUS, manufactured by GlaxoSmithKline LLC, is $2.4861 per EA (NDC 00173069500), effective Aug 19, 2026.
How has the price of ADVAIR 100-50 DISKUS changed over time?
Over the history we have for it, the NADAC for ADVAIR 100-50 DISKUS has declined 29.4%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ADVAIR 100-50 DISKUS?
Since Nov 28, 2013, the NADAC for ADVAIR 100-50 DISKUS has ranged from a low of $2.4861 (Aug 19, 2026) to a high of $5.0722 (Aug 14, 2019), with a median of $4.6587 per EA.
Are there cheaper alternatives to ADVAIR 100-50 DISKUS?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, FLUTICASONE-SALMETEROL 100-50, is $1.1188 per EA — about 55% below ADVAIR 100-50 DISKUS.
Who manufactures ADVAIR 100-50 DISKUS?
ADVAIR 100-50 DISKUS (NDC 00173069500) is labeled by GlaxoSmithKline LLC, and CMS classifies it as a brand product.