Product Information
FLUTICASONE-SALMETEROL 100-50 is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $1.0736 per EA under NDC 00054032656. Its NADAC has been published 281 times since May 19, 2021.
FDA first approved this application on Dec 17, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100; 50 ug/1; ug/1
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00054032656
Classification
Generic
Dosage Form
POWDER
Route
RESPIRATORY (INHALATION)
Effective Date
9/23/2026
Active Ingredients
FLUTICASONE PROPIONATE; SALMETEROL XINAFOATEApproval Type
Generic (ANDA)
FDA Application
ANDA203433FDA Approved
12/17/2020
TE Code
AB
On Market Since
12/17/2020
Pharmacological Classes
Price Statistics
The NADAC for FLUTICASONE-SALMETEROL 100-50 has been published 281 times since May 19, 2021, and over the history we have for it it has declined 52.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0736 per EA |
|---|---|
| All-time high | $2.2558 (Jun 16, 2021) |
| All-time low | $0.8022 (May 22, 2024) |
| 52-week high | $1.1724 |
| 52-week low | $1.0736 |
| Median price | $1.2535 |
| Average price | $1.3411 |
| Largest weekly change | +53.1% (Jun 19, 2024) |
| Weeks tracked | 281 |
| Tracking since | May 19, 2021 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Hikma Pharmaceuticals USA Inc. manufacturer profile
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Drug market
fluticasone propionate and salmeterol market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of FLUTICASONE-SALMETEROL 100-50?
The current National Average Drug Acquisition Cost (NADAC) for FLUTICASONE-SALMETEROL 100-50, manufactured by Hikma Pharmaceuticals USA Inc., is $1.0736 per EA (NDC 00054032656), effective Sep 30, 2026.
How has the price of FLUTICASONE-SALMETEROL 100-50 changed over time?
Over the history we have for it, the NADAC for FLUTICASONE-SALMETEROL 100-50 has declined 52.4%. It has been tracked across 281 weekly CMS publications since May 19, 2021.
What are the highest and lowest recorded NADAC prices for FLUTICASONE-SALMETEROL 100-50?
Since May 19, 2021, the NADAC for FLUTICASONE-SALMETEROL 100-50 has ranged from a low of $0.8022 (May 22, 2024) to a high of $2.2558 (Jun 16, 2021), with a median of $1.2535 per EA.
Are there cheaper alternatives to FLUTICASONE-SALMETEROL 100-50?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as FLUTICASONE-SALMETEROL 100-50 in a comparable dosage form, but none are currently priced below it.
Who manufactures FLUTICASONE-SALMETEROL 100-50?
FLUTICASONE-SALMETEROL 100-50 (NDC 00054032656) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.