Product Information
FLUTICASONE-SALMETEROL 100-50 is a generic product labeled by Prasco Laboratories, priced at $1.0736 per EA under NDC 66993058497. Its NADAC has been published 390 times since Apr 17, 2019.
FDA first approved this application on Aug 24, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100; 50 ug/1; ug/1
Manufacturer
Prasco LaboratoriesNDC
66993058497
Classification
Generic
Dosage Form
POWDER
Route
RESPIRATORY (INHALATION)
Effective Date
9/23/2026
Active Ingredients
FLUTICASONE PROPIONATE; SALMETEROL XINAFOATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA021077FDA Approved
8/24/2000
TE Code
AB
On Market Since
2/8/2019
Pharmacological Classes
Price Statistics
The NADAC for FLUTICASONE-SALMETEROL 100-50 has been published 390 times since Apr 17, 2019, and over the history we have for it it has declined 66.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0736 per EA |
|---|---|
| All-time high | $3.2445 (May 15, 2019) |
| All-time low | $0.8022 (May 22, 2024) |
| 52-week high | $1.1724 |
| 52-week low | $1.0736 |
| Median price | $1.3995 |
| Average price | $1.5743 |
| Largest weekly change | +53.1% (Jun 19, 2024) |
| Weeks tracked | 390 |
| Tracking since | Apr 17, 2019 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Prasco Laboratories manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
fluticasone propionate and salmeterol market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of FLUTICASONE-SALMETEROL 100-50?
The current National Average Drug Acquisition Cost (NADAC) for FLUTICASONE-SALMETEROL 100-50, manufactured by Prasco Laboratories, is $1.0736 per EA (NDC 66993058497), effective Sep 30, 2026.
How has the price of FLUTICASONE-SALMETEROL 100-50 changed over time?
Over the history we have for it, the NADAC for FLUTICASONE-SALMETEROL 100-50 has declined 66.9%. It has been tracked across 390 weekly CMS publications since Apr 17, 2019.
What are the highest and lowest recorded NADAC prices for FLUTICASONE-SALMETEROL 100-50?
Since Apr 17, 2019, the NADAC for FLUTICASONE-SALMETEROL 100-50 has ranged from a low of $0.8022 (May 22, 2024) to a high of $3.2445 (May 15, 2019), with a median of $1.3995 per EA.
Are there cheaper alternatives to FLUTICASONE-SALMETEROL 100-50?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as FLUTICASONE-SALMETEROL 100-50 in a comparable dosage form, but none are currently priced below it.
Who manufactures FLUTICASONE-SALMETEROL 100-50?
FLUTICASONE-SALMETEROL 100-50 (NDC 66993058497) is labeled by Prasco Laboratories, and CMS classifies it as a generic product.