Product Information

ADVAIR 500-50 DISKUS is a brand product labeled by GlaxoSmithKline LLC, priced at $4.2282 per EA under NDC 00173069700. Its NADAC has been published 657 times since Nov 28, 2013.

ADVAIR 500-50 DISKUS

fluticasone propionate and salmeterol
$4.2282per EA

Strength

500; 50 ug/1; ug/1

NDC

00173069700

Classification

Brand

Dosage Form

POWDER

Route

RESPIRATORY (INHALATION)

Last Updated

6/17/2026

Approval Type

New Drug (NDA)

FDA Application

NDA021077

On Market Since

3/5/2001

Pharmacological Classes

Adrenergic beta2-Agonists
Corticosteroid Hormone Receptor Agonists
Corticosteroid
beta2-Adrenergic Agonist

Price Statistics

The NADAC for ADVAIR 500-50 DISKUS has been published 657 times since Nov 28, 2013, and over the history we have for it it has declined 26.5%. The table below summarizes its recorded NADAC range and movement.

Current price$4.2282 per EA
All-time high$8.2928 (Feb 16, 2022)
All-time low$4.2280 (Feb 18, 2026)
52-week high$4.2351
52-week low$4.2280
Median price$7.6189
Average price$6.9866
Largest weekly change-48.8% (Dec 27, 2023)
Weeks tracked657
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

-0.0%

3M

-0.0%

6M

-0.0%

1Y

-0.2%

3Y

-48.9%

5Y

-49.0%

All

-26.5%

Generic Alternatives

The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 62% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ADVAIR 500-50 DISKUS?

The current National Average Drug Acquisition Cost (NADAC) for ADVAIR 500-50 DISKUS, manufactured by GlaxoSmithKline LLC, is $4.2282 per EA (NDC 00173069700), effective Jun 24, 2026.

How has the price of ADVAIR 500-50 DISKUS changed over time?

Over the history we have for it, the NADAC for ADVAIR 500-50 DISKUS has declined 26.5%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for ADVAIR 500-50 DISKUS?

Since Nov 28, 2013, the NADAC for ADVAIR 500-50 DISKUS has ranged from a low of $4.2280 (Feb 18, 2026) to a high of $8.2928 (Feb 16, 2022), with a median of $7.6189 per EA.

Are there cheaper alternatives to ADVAIR 500-50 DISKUS?

Yes. 5 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, FLUTICASONE-SALMETEROL 500-50, is $1.6120 per EA — about 62% below ADVAIR 500-50 DISKUS.

Who manufactures ADVAIR 500-50 DISKUS?

ADVAIR 500-50 DISKUS (NDC 00173069700) is labeled by GlaxoSmithKline LLC, and CMS classifies it as a brand product.