Product Information

FLUTICASONE-SALMETEROL 500-50 is a generic product labeled by Prasco Laboratories, priced at $1.6120 per EA under NDC 66993058697. Its NADAC has been published 376 times since Apr 17, 2019.

FLUTICASONE-SALMETEROL 500-50

fluticasone propionate and salmeterol
$1.6120per EA

Strength

500; 50 ug/1; ug/1

NDC

66993058697

Classification

Generic

Dosage Form

POWDER

Route

RESPIRATORY (INHALATION)

Last Updated

6/17/2026

Approval Type

Authorized Generic (NDA)

FDA Application

NDA021077

On Market Since

2/8/2019

Pharmacological Classes

Adrenergic beta2-Agonists
Corticosteroid Hormone Receptor Agonists
Corticosteroid
beta2-Adrenergic Agonist

Price Statistics

The NADAC for FLUTICASONE-SALMETEROL 500-50 has been published 376 times since Apr 17, 2019, and over the history we have for it it has declined 69.1%. The table below summarizes its recorded NADAC range and movement.

Current price$1.6120 per EA
All-time high$5.2104 (May 15, 2019)
All-time low$1.4573 (Jul 17, 2024)
52-week high$1.8626
52-week low$1.6120
Median price$2.9640
Average price$2.7915
Largest weekly change+44.0% (Aug 21, 2024)
Weeks tracked376
Tracking sinceApr 17, 2019

Price History

1W

0.0%

1M

-1.8%

3M

-3.8%

6M

-9.6%

1Y

-13.5%

3Y

-39.1%

5Y

-53.1%

All

-69.1%

Generic Alternatives

The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of FLUTICASONE-SALMETEROL 500-50?

The current National Average Drug Acquisition Cost (NADAC) for FLUTICASONE-SALMETEROL 500-50, manufactured by Prasco Laboratories, is $1.6120 per EA (NDC 66993058697), effective Jun 24, 2026.

How has the price of FLUTICASONE-SALMETEROL 500-50 changed over time?

Over the history we have for it, the NADAC for FLUTICASONE-SALMETEROL 500-50 has declined 69.1%. It has been tracked across 376 weekly CMS publications since Apr 17, 2019.

What are the highest and lowest recorded NADAC prices for FLUTICASONE-SALMETEROL 500-50?

Since Apr 17, 2019, the NADAC for FLUTICASONE-SALMETEROL 500-50 has ranged from a low of $1.4573 (Jul 17, 2024) to a high of $5.2104 (May 15, 2019), with a median of $2.9640 per EA.

Are there cheaper alternatives to FLUTICASONE-SALMETEROL 500-50?

4 NADAC-published products share the same active ingredient, strength, and dosage form as FLUTICASONE-SALMETEROL 500-50, but none are currently priced below it.

Who manufactures FLUTICASONE-SALMETEROL 500-50?

FLUTICASONE-SALMETEROL 500-50 (NDC 66993058697) is labeled by Prasco Laboratories, and CMS classifies it as a generic product.