Product Information
FLUTICASONE-SALMETEROL 500-50 is a generic product labeled by Prasco Laboratories, priced at $1.6494 per EA under NDC 66993058697. Its NADAC has been published 384 times since Apr 17, 2019.
FDA first approved this application on Aug 24, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500; 50 ug/1; ug/1
Manufacturer
Prasco LaboratoriesNDC
66993058697
Classification
Generic
Dosage Form
POWDER
Route
RESPIRATORY (INHALATION)
Effective Date
8/19/2026
Active Ingredients
FLUTICASONE PROPIONATE; SALMETEROL XINAFOATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA021077FDA Approved
8/24/2000
TE Code
AB
On Market Since
2/8/2019
Pharmacological Classes
Price Statistics
The NADAC for FLUTICASONE-SALMETEROL 500-50 has been published 384 times since Apr 17, 2019, and over the history we have for it it has declined 68.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.6494 per EA |
|---|---|
| All-time high | $5.2104 (May 15, 2019) |
| All-time low | $1.4573 (Jul 17, 2024) |
| 52-week high | $1.7934 |
| 52-week low | $1.6120 |
| Median price | $2.9630 |
| Average price | $2.7670 |
| Largest weekly change | +44.0% (Aug 21, 2024) |
| Weeks tracked | 384 |
| Tracking since | Apr 17, 2019 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of FLUTICASONE-SALMETEROL 500-50?
The current National Average Drug Acquisition Cost (NADAC) for FLUTICASONE-SALMETEROL 500-50, manufactured by Prasco Laboratories, is $1.6494 per EA (NDC 66993058697), effective Aug 19, 2026.
How has the price of FLUTICASONE-SALMETEROL 500-50 changed over time?
Over the history we have for it, the NADAC for FLUTICASONE-SALMETEROL 500-50 has declined 68.3%. It has been tracked across 384 weekly CMS publications since Apr 17, 2019.
What are the highest and lowest recorded NADAC prices for FLUTICASONE-SALMETEROL 500-50?
Since Apr 17, 2019, the NADAC for FLUTICASONE-SALMETEROL 500-50 has ranged from a low of $1.4573 (Jul 17, 2024) to a high of $5.2104 (May 15, 2019), with a median of $2.9630 per EA.
Are there cheaper alternatives to FLUTICASONE-SALMETEROL 500-50?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as FLUTICASONE-SALMETEROL 500-50 in a comparable dosage form, but none are currently priced below it.
Who manufactures FLUTICASONE-SALMETEROL 500-50?
FLUTICASONE-SALMETEROL 500-50 (NDC 66993058697) is labeled by Prasco Laboratories, and CMS classifies it as a generic product.