Product Information
FLUTICASONE-SALMETEROL 500-50 is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $1.6494 per EA under NDC 00054032856. Its NADAC has been published 129 times since Mar 6, 2024.
FDA first approved this application on Dec 17, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500; 50 ug/1; ug/1
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00054032856
Classification
Generic
Dosage Form
POWDER
Route
RESPIRATORY (INHALATION)
Effective Date
8/19/2026
Active Ingredients
FLUTICASONE PROPIONATE; SALMETEROL XINAFOATEApproval Type
Generic (ANDA)
FDA Application
ANDA203433FDA Approved
12/17/2020
TE Code
AB
On Market Since
12/17/2020
Pharmacological Classes
Price Statistics
The NADAC for FLUTICASONE-SALMETEROL 500-50 has been published 129 times since Mar 6, 2024, and over the history we have for it it has declined 40.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.6494 per EA |
|---|---|
| All-time high | $2.7582 (Mar 13, 2024) |
| All-time low | $1.4573 (Jul 17, 2024) |
| 52-week high | $1.7934 |
| 52-week low | $1.6120 |
| Median price | $1.7800 |
| Average price | $1.7995 |
| Largest weekly change | +44.0% (Aug 21, 2024) |
| Weeks tracked | 129 |
| Tracking since | Mar 6, 2024 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of FLUTICASONE-SALMETEROL 500-50?
The current National Average Drug Acquisition Cost (NADAC) for FLUTICASONE-SALMETEROL 500-50, manufactured by Hikma Pharmaceuticals USA Inc., is $1.6494 per EA (NDC 00054032856), effective Aug 19, 2026.
How has the price of FLUTICASONE-SALMETEROL 500-50 changed over time?
Over the history we have for it, the NADAC for FLUTICASONE-SALMETEROL 500-50 has declined 40.2%. It has been tracked across 129 weekly CMS publications since Mar 6, 2024.
What are the highest and lowest recorded NADAC prices for FLUTICASONE-SALMETEROL 500-50?
Since Mar 6, 2024, the NADAC for FLUTICASONE-SALMETEROL 500-50 has ranged from a low of $1.4573 (Jul 17, 2024) to a high of $2.7582 (Mar 13, 2024), with a median of $1.7800 per EA.
Are there cheaper alternatives to FLUTICASONE-SALMETEROL 500-50?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as FLUTICASONE-SALMETEROL 500-50 in a comparable dosage form, but none are currently priced below it.
Who manufactures FLUTICASONE-SALMETEROL 500-50?
FLUTICASONE-SALMETEROL 500-50 (NDC 00054032856) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.