Product Information
NEXIUM DR 40 MG CAPSULE is a brand product labeled by AstraZeneca Pharmaceuticals LP, priced at $8.7820 per EA under NDC 00186504031. Its NADAC has been published 657 times since Nov 28, 2013.
FDA first approved this application on Feb 20, 2001. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Esomeprazole magnesium market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
40 mg/1
Manufacturer
AstraZeneca Pharmaceuticals LPNDC
00186504031
Classification
Brand
Dosage Form
CAPSULE, DELAYED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ESOMEPRAZOLE MAGNESIUM TRIHYDRATEApproval Type
New Drug (NDA)
FDA Application
NDA021153FDA Approved
2/20/2001
TE Code
AB
On Market Since
3/19/2001
Pharmacological Classes
Price Statistics
The NADAC for NEXIUM DR 40 MG CAPSULE has been published 657 times since Nov 28, 2013, and over the history we have for it it has risen 20.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $8.7820 per EA |
|---|---|
| All-time high | $8.8149 (Jun 14, 2023) |
| All-time low | $7.3096 (Nov 28, 2013) |
| 52-week high | $8.8009 |
| 52-week low | $8.7820 |
| Median price | $8.1131 |
| Average price | $8.3689 |
| Largest weekly change | +6.0% (Jul 15, 2020) |
| Weeks tracked | 657 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of NEXIUM DR 40 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for NEXIUM DR 40 MG CAPSULE, manufactured by AstraZeneca Pharmaceuticals LP, is $8.7820 per EA (NDC 00186504031), effective Aug 19, 2026.
How has the price of NEXIUM DR 40 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for NEXIUM DR 40 MG CAPSULE has risen 20.1%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for NEXIUM DR 40 MG CAPSULE?
Since Nov 28, 2013, the NADAC for NEXIUM DR 40 MG CAPSULE has ranged from a low of $7.3096 (Nov 28, 2013) to a high of $8.8149 (Jun 14, 2023), with a median of $8.1131 per EA.
Are there cheaper alternatives to NEXIUM DR 40 MG CAPSULE?
Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ESOMEPRAZOLE MAG DR 40 MG CAP, is $0.1180 per EA — about 99% below NEXIUM DR 40 MG CAPSULE.
Who manufactures NEXIUM DR 40 MG CAPSULE?
NEXIUM DR 40 MG CAPSULE (NDC 00186504031) is labeled by AstraZeneca Pharmaceuticals LP, and CMS classifies it as a brand product.