Esomeprazole Magnesium

Esomeprazole Magnesium is used to treat duodenal ulcer, esophagitis, gastroesophageal reflux, heartburn, helicobacter infections and zollinger-ellison syndrome, per the National Library of Medicine's MED-RT classification. The brand product was first FDA-approved on Feb 20, 2001, and the first generic was approved Jan 26, 2015. FDA's Orange Book lists 55 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $184 million on Esomeprazole Magnesium across 3.0 million claims for 762,000 beneficiaries.

Esomeprazole Magnesium is available as 131 NDCs from 26 manufacturers (118 generic, 13 brand), with NADAC prices from $0.12 to $9.17 per EA — the most expensive product costs about 78× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.