Product Information

ZOVIRAX 5% CREAM is a brand product labeled by Bausch Health US LLC, priced at $38.4800 per GM under NDC 00187099445. Its NADAC has been published 567 times since Nov 28, 2013.

FDA first approved this application on Dec 30, 2002. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the acyclovir market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

ZOVIRAX 5% CREAM

acyclovir
$38.4800per GM
High Outlier

Strength

50 mg/g

NDC

00187099445

Classification

Brand

Dosage Form

CREAM

Route

TOPICAL

Effective Date

9/17/2025

Active Ingredients

ACYCLOVIR

Approval Type

New Drug (NDA)

FDA Application

NDA021478

FDA Approved

12/30/2002

TE Code

AB

On Market Since

12/30/2002

Price Statistics

The NADAC for ZOVIRAX 5% CREAM has been published 567 times since Nov 28, 2013, and over the history we have for it it has declined 57.8%. The table below summarizes its recorded NADAC range and movement.

Current price$38.4800 per GM
All-time high$162.4437 (Jul 21, 2021)
All-time low$38.2232 (May 22, 2024)
52-week high$38.4800
52-week low$38.4400
Median price$129.2022
Average price$106.6359
Largest weekly change-76.3% (Jul 28, 2021)
Weeks tracked567
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

+0.1%

3Y

+0.6%

5Y

-0.0%

All

-57.8%

Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 76% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 76%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of ZOVIRAX 5% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for ZOVIRAX 5% CREAM, manufactured by Bausch Health US LLC, is $38.4800 per GM (NDC 00187099445), effective Oct 1, 2025.

How has the price of ZOVIRAX 5% CREAM changed over time?

Over the history we have for it, the NADAC for ZOVIRAX 5% CREAM has declined 57.8%. It has been tracked across 567 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for ZOVIRAX 5% CREAM?

Since Nov 28, 2013, the NADAC for ZOVIRAX 5% CREAM has ranged from a low of $38.2232 (May 22, 2024) to a high of $162.4437 (Jul 21, 2021), with a median of $129.2022 per GM.

Are there cheaper alternatives to ZOVIRAX 5% CREAM?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ACYCLOVIR 5% CREAM, is $9.1076 per GM — about 76% below ZOVIRAX 5% CREAM.

Who manufactures ZOVIRAX 5% CREAM?

ZOVIRAX 5% CREAM (NDC 00187099445) is labeled by Bausch Health US LLC, and CMS classifies it as a brand product.