Drug Markets/Acyclovir

Acyclovir

87 NDCs across 31 manufacturers|85 Generic,2 Brand

Acyclovir is used to treat aids-related opportunistic infections, chickenpox, herpes simplex encephalitis, epstein-barr virus infections, herpes genitalis and herpes labialis, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved on Mar 29, 1982, and the first generic was approved Apr 22, 1997. FDA's Orange Book lists 52 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $37 million on Acyclovir across 2.0 million claims for 696,000 beneficiaries.

Acyclovir is available as 87 NDCs from 31 manufacturers (85 generic, 2 brand), with NADAC prices from $0.08 to $0.19 per EA — the most expensive product costs about 2.5× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

87

85G / 2B

Manufacturers

31

competing in market

Price Spread

$0.08 – $0.19

per EA, 54 of 87 NDCs

7d Activity

123↑87↓-123 flat

avg +1.3% WoW · of 87 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Explore this market from other angles

Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.

Manufacturer Breakdown

31 manufacturers producing ACYCLOVIR(7 pricing outliers)

Drug Portfolio

87 NDCs total, 87 shown

Drug ↕Price 7d Change ↕
ZOVIRAX 5% CREAM
$38.4800
per GM
—
ACYCLOVIR 5% CREAM
$8.9916
per GM
-1.27%
ACYCLOVIR 5% CREAM
$8.9916
per GM
-1.27%
ACYCLOVIR 5% CREAM
$8.9916
per GM
-1.27%
ACYCLOVIR 5% CREAM
$8.9916
per GM
-1.27%
ACYCLOVIR 5% CREAM
$8.9916
per GM
-1.27%
ACYCLOVIR 5% CREAM
$8.9916
per GM
-1.27%
ZOVIRAX 5% OINTMENT
$4.7770
per GM
—
ACYCLOVIR 5% OINTMENT
$1.0593
per GM
—
ACYCLOVIR 5% OINTMENT
$0.9790
per GM
—
ACYCLOVIR 5% OINTMENT
$0.5808
per GM
—
ACYCLOVIR 5% OINTMENT
$0.5221
per GM
-2.62%
ACYCLOVIR 5% OINTMENT
$0.5221
per GM
-2.62%
ACYCLOVIR 5% OINTMENT
$0.5221
per GM
-2.62%
ACYCLOVIR 5% OINTMENT
$0.5221
per GM
-2.62%
ACYCLOVIR 5% OINTMENT
$0.5221
per GM
-2.62%
ACYCLOVIR 5% OINTMENT
$0.5221
per GM
-2.62%
ACYCLOVIR 5% OINTMENT
$0.5221
per GM
-2.62%
ACYCLOVIR 5% OINTMENT
$0.3458
per GM
+1.09%
ACYCLOVIR 5% OINTMENT
$0.3458
per GM
+1.09%
ACYCLOVIR 5% OINTMENT
$0.3458
per GM
+1.09%
ACYCLOVIR 5% OINTMENT
$0.3458
per GM
+1.09%
ACYCLOVIR 5% OINTMENT
$0.3458
per GM
+1.09%
ACYCLOVIR 5% OINTMENT
$0.3458
per GM
+1.09%
ACYCLOVIR 5% OINTMENT
$0.3458
per GM
+1.09%
ACYCLOVIR 5% OINTMENT
$0.3458
per GM
+1.09%
ACYCLOVIR 5% OINTMENT
$0.3149
per GM
—
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1940
per EA
+5.05%
ACYCLOVIR 800 MG TABLET
$0.1860
per EA
—
ACYCLOVIR 800 MG TABLET
$0.1860
per EA
—
ACYCLOVIR 800 MG TABLET
$0.1589
per EA
—
ACYCLOVIR 800 MG TABLET
$0.1589
per EA
—
ACYCLOVIR 400 MG TABLET
$0.1022
per EA
—
ACYCLOVIR 400 MG TABLET
$0.1022
per EA
—
ACYCLOVIR 200 MG CAPSULE
$0.1021
per EA
—
ACYCLOVIR 200 MG CAPSULE
$0.0977
per EA
+0.41%
ACYCLOVIR 200 MG CAPSULE
$0.0977
per EA
+0.41%
ACYCLOVIR 200 MG CAPSULE
$0.0977
per EA
+0.41%
ACYCLOVIR 200 MG CAPSULE
$0.0977
per EA
+0.41%
ACYCLOVIR 200 MG CAPSULE
$0.0977
per EA
+0.41%
ACYCLOVIR 200 MG CAPSULE
$0.0977
per EA
+0.41%
ACYCLOVIR 200 MG CAPSULE
$0.0977
per EA
+0.41%
ACYCLOVIR 200 MG CAPSULE
$0.0977
per EA
+0.41%
ACYCLOVIR 200 MG CAPSULE
$0.0977
per EA
+0.41%
ACYCLOVIR 200 MG CAPSULE
$0.0977
per EA
+0.41%
ACYCLOVIR 200 MG CAPSULE
$0.0977
per EA
+0.41%
ACYCLOVIR 200 MG CAPSULE
$0.0973
per EA
—
ACYCLOVIR 200 MG CAPSULE
$0.0971
per EA
—
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0962
per EA
-2.32%
ACYCLOVIR 400 MG TABLET
$0.0779
per EA
—
ACYCLOVIR 400 MG TABLET
$0.0779
per EA
—
ACYCLOVIR 200 MG/5 ML SUSP
$0.0764
per ML
+10.19%
ACYCLOVIR 200 MG/5 ML SUSP
$0.0764
per ML
+10.19%
ACYCLOVIR 200 MG/5 ML SUSP
$0.0764
per ML
+10.19%
ACYCLOVIR 200 MG/5 ML SUSP
$0.0764
per ML
+10.19%
ACYCLOVIR 200 MG/5 ML SUSP
$0.0764
per ML
+10.19%
ACYCLOVIR 200 MG/5 ML SUSP
$0.0764
per ML
+10.19%

Frequently Asked Questions

What is Acyclovir used to treat?

Acyclovir is used to treat aids-related opportunistic infections, chickenpox, herpes simplex encephalitis, epstein-barr virus infections, herpes genitalis and herpes labialis, per the National Library of Medicine's MED-RT classification.

When did Acyclovir become available as a generic?

FDA approved the first generic Acyclovir (ANDA) on Apr 22, 1997. The Orange Book currently lists 52 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How much does Medicare spend on Acyclovir?

In 2024, Medicare Part D spent $37 million on Acyclovir across 2.0 million claims for 696,000 beneficiaries.

How many Acyclovir products are on the market?

The Acyclovir drug market contains 87 NDCs from 31 manufacturers — 85 generic and 2 brand products.

What is the price range for Acyclovir?

NADAC reference prices for Acyclovir range from $0.0779 to $0.1940 per EA — the most expensive product costs about 2.5× the cheapest. 33 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.

Which manufacturers make Acyclovir?

31 manufacturers list Acyclovir in NADAC. Ranked by number of NDCs, the largest are Heritage Pharmaceuticals Inc. (6), Carlsbad Technology Inc. (6), Viona Pharmaceuticals Inc. (5), Camber Pharmaceuticals Inc. (5), Nivagen Pharmaceuticals Inc. (5).

How has the price of Acyclovir changed recently?

Over the past 7 days, 123 Acyclovir NDCs rose and 87 fell, with a market-wide average change of +1.3%.