Product Information
HYDROCHLOROTHIAZIDE 12.5 MG TB is a generic product labeled by Actavis Pharma, Inc., priced at $0.0373 per EA under NDC 00228282096. Its NADAC has been published 131 times since Feb 21, 2024.
FDA first approved this application on Feb 27, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
12.5 mg/1
Manufacturer
Actavis Pharma, Inc.NDC
00228282096
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
HYDROCHLOROTHIAZIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040707FDA Approved
2/27/2007
TE Code
AB
On Market Since
3/12/2007
Pharmacological Classes
Price Statistics
The NADAC for HYDROCHLOROTHIAZIDE 12.5 MG TB has been published 131 times since Feb 21, 2024, and over the history we have for it it has declined 25.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0373 per EA |
|---|---|
| All-time high | $0.0505 (May 14, 2025) |
| All-time low | $0.0345 (Nov 20, 2024) |
| 52-week high | $0.0429 |
| 52-week low | $0.0373 |
| Median price | $0.0426 |
| Average price | $0.0437 |
| Largest weekly change | -28.3% (Nov 20, 2024) |
| Weeks tracked | 131 |
| Tracking since | Feb 21, 2024 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROCHLOROTHIAZIDE 12.5 MG TB?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCHLOROTHIAZIDE 12.5 MG TB, manufactured by Actavis Pharma, Inc., is $0.0373 per EA (NDC 00228282096), effective Aug 19, 2026.
How has the price of HYDROCHLOROTHIAZIDE 12.5 MG TB changed over time?
Over the history we have for it, the NADAC for HYDROCHLOROTHIAZIDE 12.5 MG TB has declined 25.6%. It has been tracked across 131 weekly CMS publications since Feb 21, 2024.
What are the highest and lowest recorded NADAC prices for HYDROCHLOROTHIAZIDE 12.5 MG TB?
Since Feb 21, 2024, the NADAC for HYDROCHLOROTHIAZIDE 12.5 MG TB has ranged from a low of $0.0345 (Nov 20, 2024) to a high of $0.0505 (May 14, 2025), with a median of $0.0426 per EA.
Are there cheaper alternatives to HYDROCHLOROTHIAZIDE 12.5 MG TB?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as HYDROCHLOROTHIAZIDE 12.5 MG TB in a comparable dosage form, but none are currently priced below it.
Who manufactures HYDROCHLOROTHIAZIDE 12.5 MG TB?
HYDROCHLOROTHIAZIDE 12.5 MG TB (NDC 00228282096) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.