Product Information
HYDROCHLOROTHIAZIDE 12.5 MG TB is a generic product labeled by Unichem Pharmaceuticals (USA) Inc., priced at $0.0340 per EA under NDC 29300048501. Its NADAC has been published 53 times since Oct 1, 2025.
FDA first approved this application on Aug 15, 2008. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
12.5 mg/1
Manufacturer
Unichem Pharmaceuticals (USA) Inc.NDC
29300048501
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
HYDROCHLOROTHIAZIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040907FDA Approved
8/15/2008
TE Code
AB
On Market Since
4/3/2025
Pharmacological Classes
Price Statistics
The NADAC for HYDROCHLOROTHIAZIDE 12.5 MG TB has been published 53 times since Oct 1, 2025, and over the history we have for it it has declined 20.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0340 per EA |
|---|---|
| All-time high | $0.0427 (Oct 15, 2025) |
| All-time low | $0.0340 (Sep 23, 2026) |
| 52-week high | $0.0427 |
| 52-week low | $0.0340 |
| Median price | $0.0408 |
| Average price | $0.0401 |
| Largest weekly change | -8.9% (Sep 23, 2026) |
| Weeks tracked | 53 |
| Tracking since | Oct 1, 2025 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Unichem Pharmaceuticals (USA) Inc. manufacturer profile
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Drug market
Hydrochlorothiazide market comparison
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Therapeutic class
Thiazide Diuretic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of HYDROCHLOROTHIAZIDE 12.5 MG TB?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCHLOROTHIAZIDE 12.5 MG TB, manufactured by Unichem Pharmaceuticals (USA) Inc., is $0.0340 per EA (NDC 29300048501), effective Sep 30, 2026.
How has the price of HYDROCHLOROTHIAZIDE 12.5 MG TB changed over time?
Over the history we have for it, the NADAC for HYDROCHLOROTHIAZIDE 12.5 MG TB has declined 20.4%. It has been tracked across 53 weekly CMS publications since Oct 1, 2025.
What are the highest and lowest recorded NADAC prices for HYDROCHLOROTHIAZIDE 12.5 MG TB?
Since Oct 1, 2025, the NADAC for HYDROCHLOROTHIAZIDE 12.5 MG TB has ranged from a low of $0.0340 (Sep 23, 2026) to a high of $0.0427 (Oct 15, 2025), with a median of $0.0408 per EA.
Are there cheaper alternatives to HYDROCHLOROTHIAZIDE 12.5 MG TB?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as HYDROCHLOROTHIAZIDE 12.5 MG TB in a comparable dosage form, but none are currently priced below it.
Who manufactures HYDROCHLOROTHIAZIDE 12.5 MG TB?
HYDROCHLOROTHIAZIDE 12.5 MG TB (NDC 29300048501) is labeled by Unichem Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.