Product Information
ALPRAZOLAM ER 0.5 MG TABLET is a generic product labeled by Actavis Pharma, Inc., priced at $0.1573 per EA under NDC 00228308306. Its NADAC has been published 658 times since Nov 28, 2013.
FDA first approved this application on Feb 13, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/1
Manufacturer
Actavis Pharma, Inc.NDC
00228308306
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
6/17/2026
Active Ingredients
ALPRAZOLAMApproval Type
Generic (ANDA)
FDA Application
ANDA078056FDA Approved
2/13/2007
TE Code
AB
On Market Since
3/12/2007
Pharmacological Classes
Price Statistics
The NADAC for ALPRAZOLAM ER 0.5 MG TABLET has been published 658 times since Nov 28, 2013, and over the history we have for it it has declined 48.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1573 per EA |
|---|---|
| All-time high | $0.3715 (Feb 12, 2014) |
| All-time low | $0.1195 (Jun 17, 2020) |
| 52-week high | $0.1746 |
| 52-week low | $0.1515 |
| Median price | $0.1947 |
| Average price | $0.2220 |
| Largest weekly change | +38.7% (Jul 22, 2020) |
| Weeks tracked | 658 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
-1.3%
6M
-0.6%
1Y
-9.9%
3Y
-8.8%
5Y
-1.6%
All
-48.6%
Last surveyed Jul 1, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 86% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ALPRAZOLAM ER 0.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ALPRAZOLAM ER 0.5 MG TABLET, manufactured by Actavis Pharma, Inc., is $0.1573 per EA (NDC 00228308306), effective Jul 1, 2026.
How has the price of ALPRAZOLAM ER 0.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for ALPRAZOLAM ER 0.5 MG TABLET has declined 48.6%. It has been tracked across 658 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ALPRAZOLAM ER 0.5 MG TABLET?
Since Nov 28, 2013, the NADAC for ALPRAZOLAM ER 0.5 MG TABLET has ranged from a low of $0.1195 (Jun 17, 2020) to a high of $0.3715 (Feb 12, 2014), with a median of $0.1947 per EA.
Are there cheaper alternatives to ALPRAZOLAM ER 0.5 MG TABLET?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ALPRAZOLAM 0.5 MG TABLET, is $0.0223 per EA — about 86% below ALPRAZOLAM ER 0.5 MG TABLET.
Who manufactures ALPRAZOLAM ER 0.5 MG TABLET?
ALPRAZOLAM ER 0.5 MG TABLET (NDC 00228308306) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.