Product Information

ALPRAZOLAM ER 1 MG TABLET is a generic product labeled by Actavis Pharma, Inc., priced at $0.1589 per EA under NDC 00228308406. Its NADAC has been published 662 times since Nov 28, 2013.

FDA first approved this application on Feb 13, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ALPRAZOLAM ER 1 MG TABLET

Alprazolam
$0.1589per EA
Discontinued
DEA Schedule CIV

Strength

1 mg/1

NDC

00228308406

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

7/22/2026

Active Ingredients

ALPRAZOLAM

Approval Type

Generic (ANDA)

FDA Application

ANDA078056

FDA Approved

2/13/2007

TE Code

AB

On Market Since

3/12/2007

Pharmacological Classes

Benzodiazepine
Benzodiazepines

Price Statistics

The NADAC for ALPRAZOLAM ER 1 MG TABLET has been published 662 times since Nov 28, 2013, and over the history we have for it it has declined 62.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1589 per EA
All-time high$0.4884 (Apr 13, 2016)
All-time low$0.1287 (Nov 20, 2024)
52-week high$0.1856
52-week low$0.1589
Median price$0.2120
Average price$0.2659
Largest weekly change+34.7% (Aug 18, 2021)
Weeks tracked662
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

0.0%

3M

-12.7%

6M

-10.2%

1Y

-14.1%

3Y

-5.9%

5Y

-21.0%

All

-62.9%

Last surveyed Jul 29, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 85% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ALPRAZOLAM ER 1 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ALPRAZOLAM ER 1 MG TABLET, manufactured by Actavis Pharma, Inc., is $0.1589 per EA (NDC 00228308406), effective Jul 29, 2026.

How has the price of ALPRAZOLAM ER 1 MG TABLET changed over time?

Over the history we have for it, the NADAC for ALPRAZOLAM ER 1 MG TABLET has declined 62.9%. It has been tracked across 662 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for ALPRAZOLAM ER 1 MG TABLET?

Since Nov 28, 2013, the NADAC for ALPRAZOLAM ER 1 MG TABLET has ranged from a low of $0.1287 (Nov 20, 2024) to a high of $0.4884 (Apr 13, 2016), with a median of $0.2120 per EA.

Are there cheaper alternatives to ALPRAZOLAM ER 1 MG TABLET?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ALPRAZOLAM 1 MG TABLET, is $0.0242 per EA — about 85% below ALPRAZOLAM ER 1 MG TABLET.

Who manufactures ALPRAZOLAM ER 1 MG TABLET?

ALPRAZOLAM ER 1 MG TABLET (NDC 00228308406) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.