Product Information
CARBIDOPA-LEVODOPA 25-100 TAB is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.0724 per EA under NDC 00378008501. Its NADAC has been published 649 times since Nov 28, 2013.
FDA first approved this application on Sep 28, 2009. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25; 100 mg/1; mg/1
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378008501
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
4/22/2026
Active Ingredients
CARBIDOPA; LEVODOPAApproval Type
Generic (ANDA)
FDA Application
ANDA090324FDA Approved
9/28/2009
TE Code
AB
On Market Since
5/16/2011
Pharmacological Classes
Price Statistics
The NADAC for CARBIDOPA-LEVODOPA 25-100 TAB has been published 649 times since Nov 28, 2013, and over the history we have for it it has declined 42.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0724 per EA |
|---|---|
| All-time high | $0.1394 (Jun 15, 2022) |
| All-time low | $0.0617 (Nov 20, 2024) |
| 52-week high | $0.0876 |
| 52-week low | $0.0724 |
| Median price | $0.0972 |
| Average price | $0.1007 |
| Largest weekly change | -30.7% (Nov 20, 2024) |
| Weeks tracked | 649 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
-4.4%
1Y
-17.4%
3Y
-24.1%
5Y
-26.1%
All
-42.3%
Last surveyed Apr 29, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CARBIDOPA-LEVODOPA 25-100 TAB?
The current National Average Drug Acquisition Cost (NADAC) for CARBIDOPA-LEVODOPA 25-100 TAB, manufactured by Mylan Pharmaceuticals Inc., is $0.0724 per EA (NDC 00378008501), effective Apr 29, 2026.
How has the price of CARBIDOPA-LEVODOPA 25-100 TAB changed over time?
Over the history we have for it, the NADAC for CARBIDOPA-LEVODOPA 25-100 TAB has declined 42.3%. It has been tracked across 649 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for CARBIDOPA-LEVODOPA 25-100 TAB?
Since Nov 28, 2013, the NADAC for CARBIDOPA-LEVODOPA 25-100 TAB has ranged from a low of $0.0617 (Nov 20, 2024) to a high of $0.1394 (Jun 15, 2022), with a median of $0.0972 per EA.
Are there cheaper alternatives to CARBIDOPA-LEVODOPA 25-100 TAB?
6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CARBIDOPA-LEVODOPA 25-100 TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures CARBIDOPA-LEVODOPA 25-100 TAB?
CARBIDOPA-LEVODOPA 25-100 TAB (NDC 00378008501) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.