Product Information
METOPROLOL-HYDROCHLOROTHIAZIDE 50-25 MG TAB is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.9452 per EA under NDC 00378042401. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Aug 20, 2004. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25; 50 mg/1; mg/1
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378042401
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
HYDROCHLOROTHIAZIDE; METOPROLOL TARTRATEApproval Type
Generic (ANDA)
FDA Application
ANDA076792FDA Approved
8/20/2004
TE Code
AB
On Market Since
8/20/2004
Pharmacological Classes
Price Statistics
The NADAC for METOPROLOL-HYDROCHLOROTHIAZIDE 50-25 MG TAB has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 10.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.9452 per EA |
|---|---|
| All-time high | $1.1404 (Jun 12, 2019) |
| All-time low | $0.6260 (Jun 19, 2024) |
| 52-week high | $1.0451 |
| 52-week low | $0.9452 |
| Median price | $0.9425 |
| Average price | $0.9303 |
| Largest weekly change | +30.7% (Sep 19, 2018) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METOPROLOL-HYDROCHLOROTHIAZIDE 50-25 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for METOPROLOL-HYDROCHLOROTHIAZIDE 50-25 MG TAB, manufactured by Mylan Pharmaceuticals Inc., is $0.9452 per EA (NDC 00378042401), effective Aug 19, 2026.
How has the price of METOPROLOL-HYDROCHLOROTHIAZIDE 50-25 MG TAB changed over time?
Over the history we have for it, the NADAC for METOPROLOL-HYDROCHLOROTHIAZIDE 50-25 MG TAB has risen 10.2%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for METOPROLOL-HYDROCHLOROTHIAZIDE 50-25 MG TAB?
Since Nov 28, 2013, the NADAC for METOPROLOL-HYDROCHLOROTHIAZIDE 50-25 MG TAB has ranged from a low of $0.6260 (Jun 19, 2024) to a high of $1.1404 (Jun 12, 2019), with a median of $0.9425 per EA.
Are there cheaper alternatives to METOPROLOL-HYDROCHLOROTHIAZIDE 50-25 MG TAB?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as METOPROLOL-HYDROCHLOROTHIAZIDE 50-25 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures METOPROLOL-HYDROCHLOROTHIAZIDE 50-25 MG TAB?
METOPROLOL-HYDROCHLOROTHIAZIDE 50-25 MG TAB (NDC 00378042401) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.