Product Information
BISOPROLOL-HYDROCHLOROTHIAZIDE 5-6.25 MG TAB is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.2141 per EA under NDC 00378050301. Its NADAC has been published 574 times since Nov 28, 2013.
FDA first approved this application on Sep 25, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
BISOPROLOL-HYDROCHLOROTHIAZIDE 5-6.25 MG TAB
bisoprolol fumarate and hydrochlorothiazideStrength
5; 6.25 mg/1; mg/1
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378050301
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
BISOPROLOL FUMARATE; HYDROCHLOROTHIAZIDEApproval Type
Generic (ANDA)
FDA Application
ANDA075768FDA Approved
9/25/2000
TE Code
AB
On Market Since
2/22/2021
Pharmacological Classes
Price Statistics
The NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 5-6.25 MG TAB has been published 574 times since Nov 28, 2013, and over the history we have for it it has risen 268.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2141 per EA |
|---|---|
| All-time high | $0.4627 (Aug 28, 2019) |
| All-time low | $0.0582 (Nov 28, 2013) |
| 52-week high | $0.2167 |
| 52-week low | $0.1916 |
| Median price | $0.1972 |
| Average price | $0.1948 |
| Largest weekly change | +385.0% (Aug 22, 2018) |
| Weeks tracked | 574 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BISOPROLOL-HYDROCHLOROTHIAZIDE 5-6.25 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for BISOPROLOL-HYDROCHLOROTHIAZIDE 5-6.25 MG TAB, manufactured by Mylan Pharmaceuticals Inc., is $0.2141 per EA (NDC 00378050301), effective Aug 19, 2026.
How has the price of BISOPROLOL-HYDROCHLOROTHIAZIDE 5-6.25 MG TAB changed over time?
Over the history we have for it, the NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 5-6.25 MG TAB has risen 268.1%. It has been tracked across 574 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for BISOPROLOL-HYDROCHLOROTHIAZIDE 5-6.25 MG TAB?
Since Nov 28, 2013, the NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 5-6.25 MG TAB has ranged from a low of $0.0582 (Nov 28, 2013) to a high of $0.4627 (Aug 28, 2019), with a median of $0.1972 per EA.
Are there cheaper alternatives to BISOPROLOL-HYDROCHLOROTHIAZIDE 5-6.25 MG TAB?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BISOPROLOL-HYDROCHLOROTHIAZIDE 5-6.25 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures BISOPROLOL-HYDROCHLOROTHIAZIDE 5-6.25 MG TAB?
BISOPROLOL-HYDROCHLOROTHIAZIDE 5-6.25 MG TAB (NDC 00378050301) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.