Product Information
BISOPROLOL-HYDROCHLOROTHIAZIDE 10-6.25 MG TAB is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.2096 per EA under NDC 00378050501. Its NADAC has been published 579 times since Nov 28, 2013.
FDA first approved this application on Sep 25, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
BISOPROLOL-HYDROCHLOROTHIAZIDE 10-6.25 MG TAB
bisoprolol fumarate and hydrochlorothiazideStrength
10; 6.25 mg/1; mg/1
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378050501
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
BISOPROLOL FUMARATE; HYDROCHLOROTHIAZIDEApproval Type
Generic (ANDA)
FDA Application
ANDA075768FDA Approved
9/25/2000
TE Code
AB
On Market Since
2/22/2021
Pharmacological Classes
Price Statistics
The NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 10-6.25 MG TAB has been published 579 times since Nov 28, 2013, and over the history we have for it it has risen 196.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2096 per EA |
|---|---|
| All-time high | $0.4753 (Oct 2, 2019) |
| All-time low | $0.0650 (Nov 23, 2016) |
| 52-week high | $0.2242 |
| 52-week low | $0.2006 |
| Median price | $0.2076 |
| Average price | $0.2053 |
| Largest weekly change | +432.2% (Aug 15, 2018) |
| Weeks tracked | 579 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BISOPROLOL-HYDROCHLOROTHIAZIDE 10-6.25 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for BISOPROLOL-HYDROCHLOROTHIAZIDE 10-6.25 MG TAB, manufactured by Mylan Pharmaceuticals Inc., is $0.2096 per EA (NDC 00378050501), effective Aug 19, 2026.
How has the price of BISOPROLOL-HYDROCHLOROTHIAZIDE 10-6.25 MG TAB changed over time?
Over the history we have for it, the NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 10-6.25 MG TAB has risen 196.8%. It has been tracked across 579 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for BISOPROLOL-HYDROCHLOROTHIAZIDE 10-6.25 MG TAB?
Since Nov 28, 2013, the NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 10-6.25 MG TAB has ranged from a low of $0.0650 (Nov 23, 2016) to a high of $0.4753 (Oct 2, 2019), with a median of $0.2076 per EA.
Are there cheaper alternatives to BISOPROLOL-HYDROCHLOROTHIAZIDE 10-6.25 MG TAB?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BISOPROLOL-HYDROCHLOROTHIAZIDE 10-6.25 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures BISOPROLOL-HYDROCHLOROTHIAZIDE 10-6.25 MG TAB?
BISOPROLOL-HYDROCHLOROTHIAZIDE 10-6.25 MG TAB (NDC 00378050501) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.