Product Information
DOXEPIN 25 MG CAPSULE is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.1415 per EA under NDC 00378312501. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on May 13, 1986. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378312501
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
DOXEPIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA070791FDA Approved
5/13/1986
TE Code
AB
On Market Since
5/13/1986
Pharmacological Classes
Price Statistics
The NADAC for DOXEPIN 25 MG CAPSULE has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 23.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1415 per EA |
|---|---|
| All-time high | $0.6205 (Jan 11, 2017) |
| All-time low | $0.1216 (Nov 20, 2024) |
| 52-week high | $0.1415 |
| 52-week low | $0.1242 |
| Median price | $0.3236 |
| Average price | $0.3203 |
| Largest weekly change | +59.2% (Mar 20, 2019) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Mylan Pharmaceuticals Inc. manufacturer profile
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Drug market
doxepin hydrochloride market comparison
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Therapeutic class
Tricyclic Antidepressant class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DOXEPIN 25 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for DOXEPIN 25 MG CAPSULE, manufactured by Mylan Pharmaceuticals Inc., is $0.1415 per EA (NDC 00378312501), effective Sep 30, 2026.
How has the price of DOXEPIN 25 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for DOXEPIN 25 MG CAPSULE has declined 23.5%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for DOXEPIN 25 MG CAPSULE?
Since Nov 28, 2013, the NADAC for DOXEPIN 25 MG CAPSULE has ranged from a low of $0.1216 (Nov 20, 2024) to a high of $0.6205 (Jan 11, 2017), with a median of $0.3236 per EA.
Are there cheaper alternatives to DOXEPIN 25 MG CAPSULE?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DOXEPIN 25 MG CAPSULE in a comparable dosage form, but none are currently priced below it.
Who manufactures DOXEPIN 25 MG CAPSULE?
DOXEPIN 25 MG CAPSULE (NDC 00378312501) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.