Product Information
HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET is a generic product labeled by SpecGx LLC, priced at $0.1276 per EA under NDC 00406012312. Its NADAC has been published 452 times since Sep 13, 2017.
FDA first approved this application on Oct 20, 2000. Its Orange Book therapeutic-equivalence code is AA.
Strength
325; 5 mg/1; mg/1
Manufacturer
SpecGx LLCNDC
00406012312
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
4/22/2026
Active Ingredients
ACETAMINOPHEN; HYDROCODONE BITARTRATEApproval Type
Generic (ANDA)
FDA Application
ANDA040409FDA Approved
10/20/2000
TE Code
AA
On Market Since
10/20/2000
Pharmacological Classes
Price Statistics
The NADAC for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET has been published 452 times since Sep 13, 2017, and over the history we have for it it has risen 9.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1276 per EA |
|---|---|
| All-time high | $0.1518 (Jul 10, 2024) |
| All-time low | $0.0764 (Nov 20, 2019) |
| 52-week high | $0.1298 |
| 52-week low | $0.1273 |
| Median price | $0.1056 |
| Average price | $0.1088 |
| Largest weekly change | +33.6% (Jan 22, 2020) |
| Weeks tracked | 452 |
| Tracking since | Sep 13, 2017 |
1W
N/A
1M
N/A
3M
N/A
6M
-0.8%
1Y
-1.7%
3Y
-2.4%
5Y
+27.3%
All
+9.7%
Last surveyed May 6, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET, manufactured by SpecGx LLC, is $0.1276 per EA (NDC 00406012312), effective May 6, 2026.
How has the price of HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET changed over time?
Over the history we have for it, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET has risen 9.7%. It has been tracked across 452 weekly CMS publications since Sep 13, 2017.
What are the highest and lowest recorded NADAC prices for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET?
Since Sep 13, 2017, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET has ranged from a low of $0.0764 (Nov 20, 2019) to a high of $0.1518 (Jul 10, 2024), with a median of $0.1056 per EA.
Are there cheaper alternatives to HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET?
HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET (NDC 00406012312) is labeled by SpecGx LLC, and CMS classifies it as a generic product.