Product Information

HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET is a generic product labeled by SpecGx LLC, priced at $0.1384 per EA under NDC 00406012323. Its NADAC has been published 549 times since Feb 17, 2016.

FDA first approved this application on Oct 20, 2000. Its Orange Book therapeutic-equivalence code is AA.

HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET

HYDROCODONE BITARTRATE AND ACETAMINOPHEN
$0.1384per EA
DEA Schedule CII

Strength

325; 5 mg/1; mg/1

Manufacturer

SpecGx LLC

NDC

00406012323

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA040409

FDA Approved

10/20/2000

TE Code

AA

On Market Since

10/20/2000

Pharmacological Classes

Opioid Agonist
Opioid Agonists

Price Statistics

The NADAC for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET has been published 549 times since Feb 17, 2016, and over the history we have for it it has declined 7.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1384 per EA
All-time high$0.1518 (Jul 10, 2024)
All-time low$0.0764 (Nov 20, 2019)
52-week high$0.1388
52-week low$0.1273
Median price$0.1091
Average price$0.1128
Largest weekly change+33.6% (Jan 22, 2020)
Weeks tracked549
Tracking sinceFeb 17, 2016

Price History

1W

-0.3%

1M

-0.3%

3M

+5.7%

6M

+7.7%

1Y

+6.7%

3Y

+5.9%

5Y

+38.1%

All

-7.1%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 8% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 8%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET, manufactured by SpecGx LLC, is $0.1384 per EA (NDC 00406012323), effective Aug 19, 2026.

How has the price of HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET changed over time?

Over the history we have for it, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET has declined 7.1%. It has been tracked across 549 weekly CMS publications since Feb 17, 2016.

What are the highest and lowest recorded NADAC prices for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET?

Since Feb 17, 2016, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET has ranged from a low of $0.0764 (Nov 20, 2019) to a high of $0.1518 (Jul 10, 2024), with a median of $0.1091 per EA.

Are there cheaper alternatives to HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET, is $0.1276 per EA — about 8% below HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET.

Who manufactures HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET?

HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET (NDC 00406012323) is labeled by SpecGx LLC, and CMS classifies it as a generic product.