Product Information
OXYCODONE-ACETAMINOPHEN 5-325 MG TAB is a generic product labeled by SpecGx LLC, priced at $0.1171 per EA under NDC 00406051223. Its NADAC has been published 555 times since Feb 17, 2016.
FDA first approved this application on Dec 7, 1983. Its Orange Book therapeutic-equivalence code is AA.
Strength
325; 5 mg/1; mg/1
Manufacturer
SpecGx LLCNDC
00406051223
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ACETAMINOPHEN; OXYCODONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA087463FDA Approved
12/7/1983
TE Code
AA
On Market Since
12/7/1983
Pharmacological Classes
Price Statistics
The NADAC for OXYCODONE-ACETAMINOPHEN 5-325 MG TAB has been published 555 times since Feb 17, 2016, and over the history we have for it it has declined 23.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1171 per EA |
|---|---|
| All-time high | $0.1620 (Apr 13, 2016) |
| All-time low | $0.0776 (May 20, 2020) |
| 52-week high | $0.1228 |
| 52-week low | $0.1171 |
| Median price | $0.1051 |
| Average price | $0.1071 |
| Largest weekly change | +13.9% (Feb 22, 2023) |
| Weeks tracked | 555 |
| Tracking since | Feb 17, 2016 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
SpecGx LLC manufacturer profile
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Drug market
oxycodone hydrochloride and acetaminophen market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of OXYCODONE-ACETAMINOPHEN 5-325 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for OXYCODONE-ACETAMINOPHEN 5-325 MG TAB, manufactured by SpecGx LLC, is $0.1171 per EA (NDC 00406051223), effective Sep 30, 2026.
How has the price of OXYCODONE-ACETAMINOPHEN 5-325 MG TAB changed over time?
Over the history we have for it, the NADAC for OXYCODONE-ACETAMINOPHEN 5-325 MG TAB has declined 23.3%. It has been tracked across 555 weekly CMS publications since Feb 17, 2016.
What are the highest and lowest recorded NADAC prices for OXYCODONE-ACETAMINOPHEN 5-325 MG TAB?
Since Feb 17, 2016, the NADAC for OXYCODONE-ACETAMINOPHEN 5-325 MG TAB has ranged from a low of $0.0776 (May 20, 2020) to a high of $0.1620 (Apr 13, 2016), with a median of $0.1051 per EA.
Are there cheaper alternatives to OXYCODONE-ACETAMINOPHEN 5-325 MG TAB?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as OXYCODONE-ACETAMINOPHEN 5-325 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures OXYCODONE-ACETAMINOPHEN 5-325 MG TAB?
OXYCODONE-ACETAMINOPHEN 5-325 MG TAB (NDC 00406051223) is labeled by SpecGx LLC, and CMS classifies it as a generic product.