Product Information
METHADONE 10 MG/ML ORAL CONC is a generic product labeled by SpecGx LLC, priced at $0.5540 per ML under NDC 00406412303. Its NADAC has been published 123 times since Apr 17, 2024.
FDA first approved this application on Aug 22, 2019. Its Orange Book therapeutic-equivalence code is AA.
Strength
10 mg/mL
Manufacturer
SpecGx LLCNDC
00406412303
Classification
Generic
Dosage Form
CONCENTRATE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METHADONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA207368FDA Approved
8/22/2019
TE Code
AA
On Market Since
6/18/2021
Pharmacological Classes
Price Statistics
The NADAC for METHADONE 10 MG/ML ORAL CONC has been published 123 times since Apr 17, 2024, and over the history we have for it it has risen 5.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5540 per ML |
|---|---|
| All-time high | $0.5560 (Aug 12, 2026) |
| All-time low | $0.4857 (May 22, 2024) |
| 52-week high | $0.5560 |
| 52-week low | $0.5336 |
| Median price | $0.5407 |
| Average price | $0.5305 |
| Largest weekly change | -7.6% (May 22, 2024) |
| Weeks tracked | 123 |
| Tracking since | Apr 17, 2024 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 90% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METHADONE 10 MG/ML ORAL CONC?
The current National Average Drug Acquisition Cost (NADAC) for METHADONE 10 MG/ML ORAL CONC, manufactured by SpecGx LLC, is $0.5540 per ML (NDC 00406412303), effective Aug 19, 2026.
How has the price of METHADONE 10 MG/ML ORAL CONC changed over time?
Over the history we have for it, the NADAC for METHADONE 10 MG/ML ORAL CONC has risen 5.4%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for METHADONE 10 MG/ML ORAL CONC?
Since Apr 17, 2024, the NADAC for METHADONE 10 MG/ML ORAL CONC has ranged from a low of $0.4857 (May 22, 2024) to a high of $0.5560 (Aug 12, 2026), with a median of $0.5407 per ML.
Are there cheaper alternatives to METHADONE 10 MG/ML ORAL CONC?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METHADONE 10 MG/ML ORAL CONC, is $0.0529 per ML — about 90% below METHADONE 10 MG/ML ORAL CONC.
Who manufactures METHADONE 10 MG/ML ORAL CONC?
METHADONE 10 MG/ML ORAL CONC (NDC 00406412303) is labeled by SpecGx LLC, and CMS classifies it as a generic product.