Product Information
METHADONE HCL 5 MG TABLET is a generic product labeled by SpecGx LLC, priced at $0.1663 per EA under NDC 00406575562. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Apr 27, 2004. Its Orange Book therapeutic-equivalence code is AA.
Strength
5 mg/1
Manufacturer
SpecGx LLCNDC
00406575562
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METHADONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040517FDA Approved
4/27/2004
TE Code
AA
On Market Since
4/27/2004
Pharmacological Classes
Price Statistics
The NADAC for METHADONE HCL 5 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 219.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1663 per EA |
|---|---|
| All-time high | $0.2148 (Apr 13, 2016) |
| All-time low | $0.0506 (Oct 22, 2014) |
| 52-week high | $0.1950 |
| 52-week low | $0.1663 |
| Median price | $0.1512 |
| Average price | $0.1458 |
| Largest weekly change | +61.3% (Dec 17, 2014) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METHADONE HCL 5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METHADONE HCL 5 MG TABLET, manufactured by SpecGx LLC, is $0.1663 per EA (NDC 00406575562), effective Aug 19, 2026.
How has the price of METHADONE HCL 5 MG TABLET changed over time?
Over the history we have for it, the NADAC for METHADONE HCL 5 MG TABLET has risen 219.7%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for METHADONE HCL 5 MG TABLET?
Since Nov 28, 2013, the NADAC for METHADONE HCL 5 MG TABLET has ranged from a low of $0.0506 (Oct 22, 2014) to a high of $0.2148 (Apr 13, 2016), with a median of $0.1512 per EA.
Are there cheaper alternatives to METHADONE HCL 5 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METHADONE HCL 5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures METHADONE HCL 5 MG TABLET?
METHADONE HCL 5 MG TABLET (NDC 00406575562) is labeled by SpecGx LLC, and CMS classifies it as a generic product.