Product Information
DESONIDE 0.05% CREAM is a generic product labeled by Actavis Pharma, Inc., priced at $0.2661 per GM under NDC 00472080415. Its NADAC has been published 662 times since Nov 28, 2013.
FDA first approved this application on Dec 14, 1984. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Actavis Pharma, Inc.NDC
00472080415
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
7/22/2026
Active Ingredients
DESONIDEApproval Type
Authorized Generic (NDA)
FDA Application
NDA019048FDA Approved
12/14/1984
TE Code
AB
On Market Since
8/1/2013
Pharmacological Classes
Price Statistics
The NADAC for DESONIDE 0.05% CREAM has been published 662 times since Nov 28, 2013, and over the history we have for it it has declined 93.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2661 per GM |
|---|---|
| All-time high | $4.1990 (Dec 11, 2013) |
| All-time low | $0.2562 (Jun 17, 2026) |
| 52-week high | $0.4448 |
| 52-week low | $0.2562 |
| Median price | $1.2224 |
| Average price | $1.6895 |
| Largest weekly change | +57.9% (Aug 21, 2024) |
| Weeks tracked | 662 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
0.0%
3M
+0.7%
6M
-16.6%
1Y
-40.2%
3Y
-48.5%
5Y
-72.7%
All
-93.7%
Last surveyed Jul 29, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 28% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DESONIDE 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for DESONIDE 0.05% CREAM, manufactured by Actavis Pharma, Inc., is $0.2661 per GM (NDC 00472080415), effective Jul 29, 2026.
How has the price of DESONIDE 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for DESONIDE 0.05% CREAM has declined 93.7%. It has been tracked across 662 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for DESONIDE 0.05% CREAM?
Since Nov 28, 2013, the NADAC for DESONIDE 0.05% CREAM has ranged from a low of $0.2562 (Jun 17, 2026) to a high of $4.1990 (Dec 11, 2013), with a median of $1.2224 per GM.
Are there cheaper alternatives to DESONIDE 0.05% CREAM?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DESONIDE 0.05% CREAM, is $0.1925 per GM — about 28% below DESONIDE 0.05% CREAM.
Who manufactures DESONIDE 0.05% CREAM?
DESONIDE 0.05% CREAM (NDC 00472080415) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.