Product Information
DESONIDE 0.05% CREAM is a generic product labeled by Actavis Pharma, Inc., priced at $0.1925 per GM under NDC 00472080460. Its NADAC has been published 662 times since Nov 28, 2013.
FDA first approved this application on Dec 14, 1984. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Actavis Pharma, Inc.NDC
00472080460
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
7/22/2026
Active Ingredients
DESONIDEApproval Type
Authorized Generic (NDA)
FDA Application
NDA019048FDA Approved
12/14/1984
TE Code
AB
On Market Since
8/1/2013
Pharmacological Classes
Price Statistics
The NADAC for DESONIDE 0.05% CREAM has been published 662 times since Nov 28, 2013, and over the history we have for it it has declined 95.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1925 per GM |
|---|---|
| All-time high | $4.1692 (Jan 15, 2014) |
| All-time low | $0.1887 (Jun 17, 2026) |
| 52-week high | $0.2413 |
| 52-week low | $0.1887 |
| Median price | $1.0603 |
| Average price | $1.4913 |
| Largest weekly change | +50.8% (Feb 22, 2023) |
| Weeks tracked | 662 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
0.0%
3M
-3.6%
6M
-3.4%
1Y
-20.2%
3Y
-52.3%
5Y
-73.6%
All
-95.3%
Last surveyed Jul 29, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DESONIDE 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for DESONIDE 0.05% CREAM, manufactured by Actavis Pharma, Inc., is $0.1925 per GM (NDC 00472080460), effective Jul 29, 2026.
How has the price of DESONIDE 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for DESONIDE 0.05% CREAM has declined 95.3%. It has been tracked across 662 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for DESONIDE 0.05% CREAM?
Since Nov 28, 2013, the NADAC for DESONIDE 0.05% CREAM has ranged from a low of $0.1887 (Jun 17, 2026) to a high of $4.1692 (Jan 15, 2014), with a median of $1.0603 per GM.
Are there cheaper alternatives to DESONIDE 0.05% CREAM?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as DESONIDE 0.05% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures DESONIDE 0.05% CREAM?
DESONIDE 0.05% CREAM (NDC 00472080460) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.