Product Information
PAIN RELIEVER PLS 250-250-65 MG is a generic product labeled by Rugby Laboratories, priced at $0.0649 per EA under NDC 00536132601. Its NADAC has been published 266 times since Jul 21, 2021.
Strength
250; 250; 65 mg/1; mg/1; mg/1
Manufacturer
Rugby LaboratoriesNDC
00536132601
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ACETAMINOPHEN; ASPIRIN; CAFFEINEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M013On Market Since
6/3/2021
Pharmacological Classes
Price Statistics
The NADAC for PAIN RELIEVER PLS 250-250-65 MG has been published 266 times since Jul 21, 2021, and over the history we have for it it has risen 13.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0649 per EA |
|---|---|
| All-time high | $0.0698 (Sep 11, 2024) |
| All-time low | $0.0530 (Nov 17, 2021) |
| 52-week high | $0.0691 |
| 52-week low | $0.0635 |
| Median price | $0.0637 |
| Average price | $0.0633 |
| Largest weekly change | +17.8% (Dec 22, 2021) |
| Weeks tracked | 266 |
| Tracking since | Jul 21, 2021 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PAIN RELIEVER PLS 250-250-65 MG?
The current National Average Drug Acquisition Cost (NADAC) for PAIN RELIEVER PLS 250-250-65 MG, manufactured by Rugby Laboratories, is $0.0649 per EA (NDC 00536132601), effective Aug 19, 2026.
How has the price of PAIN RELIEVER PLS 250-250-65 MG changed over time?
Over the history we have for it, the NADAC for PAIN RELIEVER PLS 250-250-65 MG has risen 13.5%. It has been tracked across 266 weekly CMS publications since Jul 21, 2021.
What are the highest and lowest recorded NADAC prices for PAIN RELIEVER PLS 250-250-65 MG?
Since Jul 21, 2021, the NADAC for PAIN RELIEVER PLS 250-250-65 MG has ranged from a low of $0.0530 (Nov 17, 2021) to a high of $0.0698 (Sep 11, 2024), with a median of $0.0637 per EA.
Are there cheaper alternatives to PAIN RELIEVER PLS 250-250-65 MG?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PAIN RELIEVER PLS 250-250-65 MG in a comparable dosage form, but none are currently priced below it.
Who manufactures PAIN RELIEVER PLS 250-250-65 MG?
PAIN RELIEVER PLS 250-250-65 MG (NDC 00536132601) is labeled by Rugby Laboratories, and CMS classifies it as a generic product.