Product Information
PAIN RELIEVER PLS 250-250-65 MG is a generic product labeled by Rugby Laboratories, priced at $0.0663 per EA under NDC 00536132601. Its NADAC has been published 258 times since Jul 21, 2021.
Strength
250; 250; 65 mg/1; mg/1; mg/1
Manufacturer
Rugby LaboratoriesNDC
00536132601
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
ACETAMINOPHEN; ASPIRIN; CAFFEINEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M013On Market Since
6/3/2021
Pharmacological Classes
Price Statistics
The NADAC for PAIN RELIEVER PLS 250-250-65 MG has been published 258 times since Jul 21, 2021, and over the history we have for it it has risen 15.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0663 per EA |
|---|---|
| All-time high | $0.0698 (Sep 11, 2024) |
| All-time low | $0.0530 (Nov 17, 2021) |
| 52-week high | $0.0691 |
| 52-week low | $0.0635 |
| Median price | $0.0635 |
| Average price | $0.0632 |
| Largest weekly change | +17.8% (Dec 22, 2021) |
| Weeks tracked | 258 |
| Tracking since | Jul 21, 2021 |
Generic Alternatives
The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of PAIN RELIEVER PLS 250-250-65 MG?
The current National Average Drug Acquisition Cost (NADAC) for PAIN RELIEVER PLS 250-250-65 MG, manufactured by Rugby Laboratories, is $0.0663 per EA (NDC 00536132601), effective Jun 24, 2026.
How has the price of PAIN RELIEVER PLS 250-250-65 MG changed over time?
Over the history we have for it, the NADAC for PAIN RELIEVER PLS 250-250-65 MG has risen 15.9%. It has been tracked across 258 weekly CMS publications since Jul 21, 2021.
What are the highest and lowest recorded NADAC prices for PAIN RELIEVER PLS 250-250-65 MG?
Since Jul 21, 2021, the NADAC for PAIN RELIEVER PLS 250-250-65 MG has ranged from a low of $0.0530 (Nov 17, 2021) to a high of $0.0698 (Sep 11, 2024), with a median of $0.0635 per EA.
Are there cheaper alternatives to PAIN RELIEVER PLS 250-250-65 MG?
5 NADAC-published products share the same active ingredient, strength, and dosage form as PAIN RELIEVER PLS 250-250-65 MG, but none are currently priced below it.
Who manufactures PAIN RELIEVER PLS 250-250-65 MG?
PAIN RELIEVER PLS 250-250-65 MG (NDC 00536132601) is labeled by Rugby Laboratories, and CMS classifies it as a generic product.
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