Product Information

OLOPATADINE HCL 0.1% EYE DROPS is a generic product labeled by Rugby Laboratories, priced at $1.2677 per ML under NDC 00536144540. Its NADAC has been published 44 times since Oct 22, 2025.

FDA first approved this application on Jul 26, 2017.

OLOPATADINE HCL 0.1% EYE DROPS

Olopatadine Hydrochloride Ophthalmic Solution
$1.2677per ML
OTC

Strength

1 mg/mL

Manufacturer

Rugby Laboratories

NDC

00536144540

Classification

Generic

Dosage Form

SOLUTION

Route

OPHTHALMIC

Effective Date

8/19/2026

Active Ingredients

OLOPATADINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA206046

FDA Approved

7/26/2017

On Market Since

4/15/2025

Pharmacological Classes

Decreased Histamine Release
Histamine H1 Receptor Antagonists
Histamine-1 Receptor Antagonist
Histamine-1 Receptor Inhibitor
Mast Cell Stabilizer

Price Statistics

The NADAC for OLOPATADINE HCL 0.1% EYE DROPS has been published 44 times since Oct 22, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.

Current price$1.2677 per ML
All-time high$1.2895 (Nov 12, 2025)
All-time low$1.2029 (Feb 18, 2026)
52-week high$1.2895
52-week low$1.2029
Median price$1.2228
Average price$1.2294
Largest weekly change-2.9% (Nov 19, 2025)
Weeks tracked44
Tracking sinceOct 22, 2025

Price History

1W

+2.7%

1M

+2.7%

3M

+3.9%

6M

+5.4%

1Y

N/A

3Y

N/A

5Y

N/A

All

-1.7%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of OLOPATADINE HCL 0.1% EYE DROPS?

The current National Average Drug Acquisition Cost (NADAC) for OLOPATADINE HCL 0.1% EYE DROPS, manufactured by Rugby Laboratories, is $1.2677 per ML (NDC 00536144540), effective Aug 19, 2026.

How has the price of OLOPATADINE HCL 0.1% EYE DROPS changed over time?

Over the history we have for it, the NADAC for OLOPATADINE HCL 0.1% EYE DROPS has held within roughly two percent of its current level. It has been tracked across 44 weekly CMS publications since Oct 22, 2025.

What are the highest and lowest recorded NADAC prices for OLOPATADINE HCL 0.1% EYE DROPS?

Since Oct 22, 2025, the NADAC for OLOPATADINE HCL 0.1% EYE DROPS has ranged from a low of $1.2029 (Feb 18, 2026) to a high of $1.2895 (Nov 12, 2025), with a median of $1.2228 per ML.

Are there cheaper alternatives to OLOPATADINE HCL 0.1% EYE DROPS?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as OLOPATADINE HCL 0.1% EYE DROPS in a comparable dosage form, but none are currently priced below it.

Who manufactures OLOPATADINE HCL 0.1% EYE DROPS?

OLOPATADINE HCL 0.1% EYE DROPS (NDC 00536144540) is labeled by Rugby Laboratories, and CMS classifies it as a generic product.