Product Information
OLOPATADINE HCL 0.1% EYE DROPS is a generic product labeled by Rugby Laboratories, priced at $1.2737 per ML under NDC 00536144540. Its NADAC has been published 50 times since Oct 22, 2025.
FDA first approved this application on Jul 26, 2017.
Strength
1 mg/mL
Manufacturer
Rugby LaboratoriesNDC
00536144540
Classification
Generic
Dosage Form
SOLUTION
Route
OPHTHALMIC
Effective Date
9/23/2026
Active Ingredients
OLOPATADINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA206046FDA Approved
7/26/2017
On Market Since
4/15/2025
Pharmacological Classes
Price Statistics
The NADAC for OLOPATADINE HCL 0.1% EYE DROPS has been published 50 times since Oct 22, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.2737 per ML |
|---|---|
| All-time high | $1.2895 (Nov 12, 2025) |
| All-time low | $1.2029 (Feb 18, 2026) |
| 52-week high | $1.2895 |
| 52-week low | $1.2029 |
| Median price | $1.2228 |
| Average price | $1.2342 |
| Largest weekly change | -2.9% (Nov 19, 2025) |
| Weeks tracked | 50 |
| Tracking since | Oct 22, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Rugby Laboratories manufacturer profile
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Drug market
Olopatadine Hydrochloride Ophthalmic Solution market comparison
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Therapeutic class
Histamine-1 Receptor Antagonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of OLOPATADINE HCL 0.1% EYE DROPS?
The current National Average Drug Acquisition Cost (NADAC) for OLOPATADINE HCL 0.1% EYE DROPS, manufactured by Rugby Laboratories, is $1.2737 per ML (NDC 00536144540), effective Sep 30, 2026.
How has the price of OLOPATADINE HCL 0.1% EYE DROPS changed over time?
Over the history we have for it, the NADAC for OLOPATADINE HCL 0.1% EYE DROPS has held within roughly two percent of its current level. It has been tracked across 50 weekly CMS publications since Oct 22, 2025.
What are the highest and lowest recorded NADAC prices for OLOPATADINE HCL 0.1% EYE DROPS?
Since Oct 22, 2025, the NADAC for OLOPATADINE HCL 0.1% EYE DROPS has ranged from a low of $1.2029 (Feb 18, 2026) to a high of $1.2895 (Nov 12, 2025), with a median of $1.2228 per ML.
Are there cheaper alternatives to OLOPATADINE HCL 0.1% EYE DROPS?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as OLOPATADINE HCL 0.1% EYE DROPS in a comparable dosage form, but none are currently priced below it.
Who manufactures OLOPATADINE HCL 0.1% EYE DROPS?
OLOPATADINE HCL 0.1% EYE DROPS (NDC 00536144540) is labeled by Rugby Laboratories, and CMS classifies it as a generic product.