Therapeutic Classes/Histamine-1 Receptor Inhibitor

Histamine-1 Receptor Inhibitor

43 drugs across 19 manufacturers|35 Generic,8 Brand

The Histamine-1 Receptor Inhibitor class contains 43 NDCs from 19 manufacturers (35 generic, 8 brand), at an average NADAC of $2.54 per unit. Every drug, manufacturer, and price in this FDA-defined pharmacologic class is listed below.

Total Drugs

35G / 8B

Manufacturers

Avg $2.5442/unit

Avg 7d Change

-0.88%

Across 28 drugs with changes

7d Activity

10↑18↓15 flat

of 43 total drugs

Class Price Trend

Monthly average NADAC price per unit, split by generic and brand

Manufacturer Breakdown

19 manufacturers producing drugs in this therapeutic class(2 pricing outliers)

Alcon Laboratories, Inc.

Somerset Therapeutics, LLC

Strategic Sourcing Services LLC

3 drugs

$1.8350

avg/unit

Alembic Pharmaceuticals Inc.

2 drugs

$3.6563

avg/unit

Chain Drug Marketing Association

2 drugs

$3.1517

avg/unit

Rising Pharma Holdings Inc.

2 drugs

$2.1187

avg/unit

Dr. Reddy's Laboratories Inc.

BluePoint Laboratories

2 drugs

$2.9636

avg/unit

Bausch & Lomb Incorporated

2 drugs

$1.4654

avg/unit

and 7 more manufacturers

Drug Portfolio

43 drugs total, 43 shown

Drug ↕	NDC	Price	7d Change ↕	Class	Market Outlier	Manufacturer ↕
EPINASTINE HCL 0.05% EYE DROPS EPINASTINE HYDROCHLORIDE	70069000801	$14.3295 per ML	-2.90%	Generic	—	Somerset Therapeutics, LLC
RYALTRIS 665-25 MCG SPRAY olopatadine hydrochloride and mometasone furoate	59467070027	$7.6715 per GM	—	Brand	—	Hikma Specialty USA Inc.
PATADAY ONCE DAILY 0.7% DROPS OLOPATADINE HYDROCHLORIDE	00065081604	$6.2023 per ML	—	Brand OTC	—	Alcon Laboratories, Inc.
PATADAY ONCE DAILY 0.2% DROPS OLOPATADINE HYDROCHLORIDE	00065815001	$5.8929 per ML	—	Brand OTC	—	Alcon Laboratories, Inc.
OLOPATADINE HCL 0.2% EYE DROP olopatadine hydrochloride	62332050203	$4.2477 per ML	—	Generic	—	Alembic Pharmaceuticals Inc.
QC OLOPATADINE 0.2% EYE DROP Olopatadine Hydrochloride Ophthalmic	63868082125	$3.3397 per ML	—	Generic OTC	High Outlier	Chain Drug Marketing Association
EYE ALLERGY ITCH RLF 0.2% DROP Olopatadine Hydrochloride Ophthalmic	70000005301	$3.0962 per ML	—	Generic OTC	—	Cardinal Health
OLOPATADINE HCL 0.1% EYE DROPS olopatadine hydrochloride	62332050105	$3.0649 per ML	—	Generic	—	Alembic Pharmaceuticals Inc.
OLOPATADINE HCL 0.2% EYE DROP Olopatadine Hydrochloride Ophthalmic	00536130723	$2.9636 per ML	-1.11%	Generic OTC	—	Rugby Laboratories
OLOPATADINE HCL 0.2% EYE DROP olopatadine hydrochloride	16571086125	$2.9636 per ML	-1.11%	Generic OTC	—	Rising Pharma Holdings Inc.
OLOPATADINE HCL 0.2% EYE DROP Olopatadine Hydrochloride Ophthalmic	43598076402	$2.9636 per ML	-1.11%	Generic OTC	—	Dr. Reddy's Laboratories Inc.
GNP OLOPATADINE 0.2% EYE DROP OLOPATADINE HYDROCHLORIDE	46122067127	$2.9636 per ML	-1.11%	Generic OTC	—	AmerisourceBergen
OLOPATADINE HCL 0.2% EYE DROP OLOPATADINE HYDROCHLORIDE	68001053069	$2.9636 per ML	-1.11%	Generic OTC	—	BluePoint Laboratories
OLOPATADINE HCL 0.2% EYE DROP OLOPATADINE HYDROCHLORIDE	68001067492	$2.9636 per ML	-1.11%	Generic OTC	—	BluePoint Laboratories
OLOPATADINE HCL 0.2% EYE DROP Olopatadine Hydrochloride	70069049101	$2.9636 per ML	-1.11%	Generic OTC	—	Somerset Therapeutics, LLC
FT EYE ALLERGY ITCH RLF 0.2% Olopatadine Hydrochloride Ophthalmic	70677115501	$2.9636 per ML	-1.11%	Generic OTC	Low Outlier	Strategic Sourcing Services LLC
OLOPATADINE HCL 0.2% EYE DROP Olopatadine Hydrochloride Ophthalmic	83324012025	$2.9636 per ML	-1.11%	Generic OTC	High Outlier	Chain Drug Marketing Association
PATADAY TWICE DAILY 0.1% DROPS OLOPATADINE HYDROCHLORIDE	00065427401	$2.4820 per ML	—	Brand OTC	—	Alcon Laboratories, Inc.
ZADITOR 0.025% (0.035%) DROPS ketotifen fumarate	00065401105	$2.2285 per ML	+0.15%	— OTC	High Outlier	Alcon Laboratories, Inc.
CHILD'S ALAWAY 0.025% EYE DROP Ketotifen Fumarate	24208060105	$2.0833 per ML	—	Brand OTC	—	Bausch & Lomb Incorporated
OLOPATADINE HCL 0.2% EYE DROP OLOPATADINE HYDROCHLORIDE	70000071601	$1.9835 per ML	-1.06%	Generic OTC	—	Cardinal Health
ZADITOR 0.025% (0.035%) DROPS ketotifen fumarate	00065401106	$1.8700 per ML	+0.27%	— OTC	High Outlier	Alcon Laboratories, Inc.
EYE ITCH RELIEF 0.025% DROPS Ketotifen Fumarate	70000012401	$1.3223 per ML	—	Generic OTC	Low Outlier	Cardinal Health
EYE ITCH RELIEF 0.025% DROPS Ketotifen Fumarate	00536125240	$1.2940 per ML	-0.78%	Generic OTC	—	Rugby Laboratories
EYE ITCH RELIEF 0.025% DROPS ketotifen fumarate	70000052201	$1.2940 per ML	-0.78%	Generic OTC	Low Outlier	Cardinal Health
KETOTIFEN 0.025% (0.035%) DROP Ketotifen Fumarate	72485061710	$1.2940 per ML	-0.78%	Generic OTC	—	Armas Pharmaceuticals Inc.
KETOTIFEN 0.025% (0.035%) DROP KETOTIFEN FUMARATE	76385010617	$1.2940 per ML	-0.78%	Generic OTC	—	Unichem Pharmaceuticals (USA) Inc.
OLOPATADINE HCL 0.1% EYE DROPS Olopatadine Hydrochloride Ophthalmic Solution	00536144540	$1.2737 per ML	+0.47%	Generic OTC	—	Rugby Laboratories
OLOPATADINE HCL 0.1% EYE DROP olopatadine hydrochloride	16571088205	$1.2737 per ML	+0.47%	Generic OTC	—	Rising Pharma Holdings Inc.
OLOPATADINE HCL 0.1% EYE DROPS Olopatadine Hydrochloride Ophthalmic	43598076507	$1.2737 per ML	+0.47%	Generic OTC	—	Dr. Reddy's Laboratories Inc.
GNP OLOPATADINE 0.1% EYE DROPS OLOPATADINE HYDROCHLORIDE	46122067264	$1.2737 per ML	+0.47%	Generic OTC	—	AmerisourceBergen
OLOPATADINE HCL 0.1% EYE DROP Olopatadine Hydrochloride Ophthalmic Solution	70000071701	$1.2737 per ML	+0.47%	Generic OTC	—	Cardinal Health
OLOPATADINE HCL 0.1% EYE DROP Olopatadine	70069001701	$1.2737 per ML	+0.47%	Generic OTC	—	Somerset Therapeutics, LLC
OLOPATADINE HCL 0.1% EYE DROP Olopatadine Hcl	70512052005	$1.2737 per ML	+0.47%	Generic OTC	—	SOLA Pharmaceuticals LLC
FT EYE ALLERGY ITCH-RED 0.1% Olopatadine Hydrochloride ophthalmic	70677128001	$1.2737 per ML	+0.47%	Generic OTC	Low Outlier	Strategic Sourcing Services LLC
FT EYE ALLERGY ITCH-RED 0.1% Olopatadine Hydrochloride Ophthalmic	70677115601	$1.2677 per ML	—	Generic OTC	Low Outlier	Strategic Sourcing Services LLC
OLOPATADINE HCL 0.1% EYE DROPS Olopatadine Hydrochloride Ophthalmic	00536130840	$1.2228 per ML	—	Generic OTC	—	Rugby Laboratories
EYE ALLERGY ITCH-RED 0.1% DROP Olopatadine Hydrochloride Ophthalmic	70000005401	$1.2205 per ML	—	Generic OTC	—	Cardinal Health
OLOPATADINE 665 MCG NASAL SPRY Olopatadine Hydrochloride	45802010401	$0.8495 per GM	-2.11%	Generic	—	Padagis Israel Pharmaceuticals Ltd
OLOPATADINE 665 MCG NASAL SPRY olopatadine hydrochloride	60505084505	$0.8495 per GM	-2.11%	Generic	—	Apotex Corp.
OLOPATADINE 665 MCG NASAL SPRY Olopatadine Hydrochloride	65162089023	$0.8495 per GM	-2.11%	Generic	—	Amneal Pharmaceuticals LLC
ALAWAY 0.025% EYE DROPS Ketotifen Fumarate	24208060110	$0.8474 per ML	—	Brand OTC	—	Bausch & Lomb Incorporated
EYE ITCH RELIEF 0.025% DROPS ketotifen fumarate	70000052202	$0.4390 per ML	—	Generic OTC	Low Outlier	Cardinal Health

Follow this class across the site

These links connect the therapeutic class page to the specific suppliers, markets, and trend surfaces that help users keep exploring.

Top supplier

Cardinal Health manufacturer profile

Review the supplier with the strongest product footprint inside this therapeutic class.

Lead market

Olopatadine Hydrochloride Ophthalmic market page

Move from the therapeutic class into the molecule that appears most often in this class-specific portfolio.

Trend hub

Latest trend hub

Compare this class against the rest of the weekly NADAC trend surface.

Guide

Understanding NADAC pricing

Use the explainer when you need a plain-English refresher on how these class-level numbers are published and interpreted.

Frequently Asked Questions

How many drugs are in the Histamine-1 Receptor Inhibitor class?

The Histamine-1 Receptor Inhibitor class contains 43 NDCs from 19 manufacturers — 35 generic and 8 brand products.

What is the average price of Histamine-1 Receptor Inhibitor drugs?

The average NADAC for the Histamine-1 Receptor Inhibitor class is $2.5442 per unit across 43 NDCs.

Is generic cheaper than brand in the Histamine-1 Receptor Inhibitor class?

Among products priced per ML, the average generic NADAC in this class is $2.4241, versus $3.0866 for brand — generic is about 21% cheaper on average.

Which manufacturers make Histamine-1 Receptor Inhibitor drugs?

19 manufacturers make drugs in the Histamine-1 Receptor Inhibitor class. Ranked by number of NDCs, the largest are Cardinal Health (7), Alcon Laboratories, Inc. (5), Rugby Laboratories (4), Somerset Therapeutics, LLC (3), Strategic Sourcing Services LLC (3).

How has Histamine-1 Receptor Inhibitor pricing changed recently?

Over the past 7 days, 10 NDCs in this class rose and 18 fell, with a class-wide average change of -0.9%.