Product Information

OMEPRAZOLE DR 20 MG TABLET is a generic product labeled by Rugby Laboratories, priced at $0.3904 per EA under NDC 00536144888. Its NADAC has been published 42 times since Nov 5, 2025.

FDA first approved this application on Dec 4, 2007.

OMEPRAZOLE DR 20 MG TABLET

Omeprazole
$0.3904per EA
OTC

Strength

20 mg/1

Manufacturer

Rugby Laboratories

NDC

00536144888

Classification

Generic

Dosage Form

TABLET, DELAYED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

OMEPRAZOLE

Approval Type

New Drug (NDA)

FDA Application

NDA022032

FDA Approved

12/4/2007

On Market Since

4/15/2025

Pharmacological Classes

Cytochrome P450 2C19 Inhibitors
Proton Pump Inhibitor
Proton Pump Inhibitors

Price Statistics

The NADAC for OMEPRAZOLE DR 20 MG TABLET has been published 42 times since Nov 5, 2025, and over the history we have for it it has declined 4.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3904 per EA
All-time high$0.4213 (Dec 10, 2025)
All-time low$0.3904 (Aug 19, 2026)
52-week high$0.4213
52-week low$0.3904
Median price$0.3997
Average price$0.4027
Largest weekly change+3.1% (Nov 19, 2025)
Weeks tracked42
Tracking sinceNov 5, 2025

Price History

1W

-0.1%

1M

-0.1%

3M

-2.8%

6M

-2.1%

1Y

N/A

3Y

N/A

5Y

N/A

All

-4.5%

Generic Alternatives

The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of OMEPRAZOLE DR 20 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for OMEPRAZOLE DR 20 MG TABLET, manufactured by Rugby Laboratories, is $0.3904 per EA (NDC 00536144888), effective Aug 19, 2026.

How has the price of OMEPRAZOLE DR 20 MG TABLET changed over time?

Over the history we have for it, the NADAC for OMEPRAZOLE DR 20 MG TABLET has declined 4.5%. It has been tracked across 42 weekly CMS publications since Nov 5, 2025.

What are the highest and lowest recorded NADAC prices for OMEPRAZOLE DR 20 MG TABLET?

Since Nov 5, 2025, the NADAC for OMEPRAZOLE DR 20 MG TABLET has ranged from a low of $0.3904 (Aug 19, 2026) to a high of $0.4213 (Dec 10, 2025), with a median of $0.3997 per EA.

Are there cheaper alternatives to OMEPRAZOLE DR 20 MG TABLET?

11 manufacturers publish a NADAC-priced product with the same active ingredient and strength as OMEPRAZOLE DR 20 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures OMEPRAZOLE DR 20 MG TABLET?

OMEPRAZOLE DR 20 MG TABLET (NDC 00536144888) is labeled by Rugby Laboratories, and CMS classifies it as a generic product.