Product Information
TOPIRAMATE 25 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.0268 per EA under NDC 00904692861. Its NADAC has been published 250 times since Dec 22, 2021.
FDA first approved this application on Mar 27, 2009. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904692861
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
TOPIRAMATEApproval Type
Generic (ANDA)
FDA Application
ANDA078235FDA Approved
3/27/2009
TE Code
AB
On Market Since
3/27/2009
Pharmacological Classes
Price Statistics
The NADAC for TOPIRAMATE 25 MG TABLET has been published 250 times since Dec 22, 2021, and over the history we have for it it has declined 17.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0268 per EA |
|---|---|
| All-time high | $0.0354 (Jun 14, 2023) |
| All-time low | $0.0221 (Jul 17, 2024) |
| 52-week high | $0.0270 |
| 52-week low | $0.0254 |
| Median price | $0.0297 |
| Average price | $0.0295 |
| Largest weekly change | -29.1% (Jul 17, 2024) |
| Weeks tracked | 250 |
| Tracking since | Dec 22, 2021 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Major Pharmaceuticals manufacturer profile
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Drug market
topiramate market comparison
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Trend hub
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of TOPIRAMATE 25 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for TOPIRAMATE 25 MG TABLET, manufactured by Major Pharmaceuticals, is $0.0268 per EA (NDC 00904692861), effective Sep 30, 2026.
How has the price of TOPIRAMATE 25 MG TABLET changed over time?
Over the history we have for it, the NADAC for TOPIRAMATE 25 MG TABLET has declined 17.5%. It has been tracked across 250 weekly CMS publications since Dec 22, 2021.
What are the highest and lowest recorded NADAC prices for TOPIRAMATE 25 MG TABLET?
Since Dec 22, 2021, the NADAC for TOPIRAMATE 25 MG TABLET has ranged from a low of $0.0221 (Jul 17, 2024) to a high of $0.0354 (Jun 14, 2023), with a median of $0.0297 per EA.
Are there cheaper alternatives to TOPIRAMATE 25 MG TABLET?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TOPIRAMATE 25 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures TOPIRAMATE 25 MG TABLET?
TOPIRAMATE 25 MG TABLET (NDC 00904692861) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.