Product Information
NICOTINE 21 MG/24HR PATCH is a generic product labeled by Rugby Laboratories, priced at $1.8725 per EA under NDC 00536589688. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Oct 20, 1997.
Strength
21 mg/24h
Manufacturer
Rugby LaboratoriesNDC
00536589688
Classification
Generic
Dosage Form
PATCH
Route
TRANSDERMAL
Effective Date
9/23/2026
Active Ingredients
NICOTINEApproval Type
Generic (ANDA)
FDA Application
ANDA074612FDA Approved
10/20/1997
On Market Since
6/25/2024
Pharmacological Classes
Price Statistics
The NADAC for NICOTINE 21 MG/24HR PATCH has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 3.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.8725 per EA |
|---|---|
| All-time high | $1.8957 (Aug 13, 2014) |
| All-time low | $1.2564 (Apr 17, 2024) |
| 52-week high | $1.8725 |
| 52-week low | $1.4808 |
| Median price | $1.6736 |
| Average price | $1.6583 |
| Largest weekly change | -20.6% (Apr 17, 2024) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 17% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Rugby Laboratories manufacturer profile
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Drug market
Nicotine market comparison
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Therapeutic class
Cholinergic Nicotinic Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of NICOTINE 21 MG/24HR PATCH?
The current National Average Drug Acquisition Cost (NADAC) for NICOTINE 21 MG/24HR PATCH, manufactured by Rugby Laboratories, is $1.8725 per EA (NDC 00536589688), effective Sep 30, 2026.
How has the price of NICOTINE 21 MG/24HR PATCH changed over time?
Over the history we have for it, the NADAC for NICOTINE 21 MG/24HR PATCH has risen 3.2%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for NICOTINE 21 MG/24HR PATCH?
Since Nov 28, 2013, the NADAC for NICOTINE 21 MG/24HR PATCH has ranged from a low of $1.2564 (Apr 17, 2024) to a high of $1.8957 (Aug 13, 2014), with a median of $1.6736 per EA.
Are there cheaper alternatives to NICOTINE 21 MG/24HR PATCH?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SM NICOTINE 21 MG/24HR PATCH, is $1.5540 per EA — about 17% below NICOTINE 21 MG/24HR PATCH.
Who manufactures NICOTINE 21 MG/24HR PATCH?
NICOTINE 21 MG/24HR PATCH (NDC 00536589688) is labeled by Rugby Laboratories, and CMS classifies it as a generic product.