Nicotine
38 NDCs across 6 manufacturers|28 Generic,10 Brand
Nicotine is used to treat ulcerative colitis and tobacco use disorder, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on Mar 22, 1996, and the first generic was approved Oct 20, 1997. In 2024, Medicare Part D spent $8 million on Nicotine across 12,000 claims for 5,133 beneficiaries.
Nicotine is available as 38 NDCs from 6 manufacturers (28 generic, 10 brand), with NADAC prices from $1.38 to $3.12 per EA — the most expensive product costs about 2.3× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
38
28G / 10B
Manufacturers
6
competing in market
Price Spread
$1.38 – $3.12
per EA, 37 of 38 NDCs
7d Activity
avg +4.2% WoW · of 38 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.
Top supplier
Rugby Laboratories manufacturer profile
Open the supplier page for the manufacturer with the strongest footprint in this market.
Lead class
Cholinergic Nicotinic Agonist class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
6 manufacturers producing NICOTINE(1 pricing outlier)
Frequently Asked Questions
What is Nicotine used to treat?
Nicotine is used to treat ulcerative colitis and tobacco use disorder, per the National Library of Medicine's MED-RT classification.
When did Nicotine become available as a generic?
FDA approved the first generic Nicotine (ANDA) on Oct 20, 1997.
How much does Medicare spend on Nicotine?
In 2024, Medicare Part D spent $8 million on Nicotine across 12,000 claims for 5,133 beneficiaries.
How many Nicotine products are on the market?
The Nicotine drug market contains 38 NDCs from 6 manufacturers — 28 generic and 10 brand products.
What is the price range for Nicotine?
NADAC reference prices for Nicotine range from $1.3769 to $3.1231 per EA — the most expensive product costs about 2.3× the cheapest. 1 additional product is priced per a different unit (e.g. liquids per ML) and isn't directly comparable.
Is generic Nicotine cheaper than brand?
The average generic NADAC for Nicotine is $1.7908 per EA, versus $3.0648 for brand-labeled products — generic is about 42% cheaper on average.
Which manufacturers make Nicotine?
6 manufacturers list Nicotine in NADAC. Ranked by number of NDCs, the largest are Rugby Laboratories (11), Haleon US Holdings LLC (9), Dr. Reddy's Laboratories Inc. (8), Strategic Sourcing Services LLC (7), Chain Drug Marketing Association (2).
How has the price of Nicotine changed recently?
Over the past 7 days, 22 Nicotine NDCs rose and 2 fell, with a market-wide average change of +4.2%.