Product Information
DOXYCYCLINE HYC DR 200 MG TAB is a generic product labeled by Actavis Pharma, Inc., priced at $5.1722 per EA under NDC 00591457560. Its NADAC has been published 107 times since Sep 18, 2024.
FDA first approved this application on Dec 14, 2011. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
200 mg/1
Manufacturer
Actavis Pharma, Inc.NDC
00591457560
Classification
Generic
Dosage Form
TABLET, DELAYED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
DOXYCYCLINE HYCLATEApproval Type
Generic (ANDA)
FDA Application
ANDA090134FDA Approved
12/14/2011
TE Code
AB
On Market Since
8/14/2019
Pharmacological Classes
Price Statistics
The NADAC for DOXYCYCLINE HYC DR 200 MG TAB has been published 107 times since Sep 18, 2024, and over the history we have for it it has risen 140.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $5.1722 per EA |
|---|---|
| All-time high | $5.7789 (Jan 14, 2026) |
| All-time low | $2.1497 (Sep 18, 2024) |
| 52-week high | $5.7789 |
| 52-week low | $3.3319 |
| Median price | $3.3319 |
| Average price | $3.4504 |
| Largest weekly change | +39.8% (Sep 23, 2026) |
| Weeks tracked | 107 |
| Tracking since | Sep 18, 2024 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Actavis Pharma, Inc. manufacturer profile
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Drug market
Doxycycline Hyclate market comparison
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Therapeutic class
Tetracycline-class Drug class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DOXYCYCLINE HYC DR 200 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for DOXYCYCLINE HYC DR 200 MG TAB, manufactured by Actavis Pharma, Inc., is $5.1722 per EA (NDC 00591457560), effective Sep 30, 2026.
How has the price of DOXYCYCLINE HYC DR 200 MG TAB changed over time?
Over the history we have for it, the NADAC for DOXYCYCLINE HYC DR 200 MG TAB has risen 140.6%. It has been tracked across 107 weekly CMS publications since Sep 18, 2024.
What are the highest and lowest recorded NADAC prices for DOXYCYCLINE HYC DR 200 MG TAB?
Since Sep 18, 2024, the NADAC for DOXYCYCLINE HYC DR 200 MG TAB has ranged from a low of $2.1497 (Sep 18, 2024) to a high of $5.7789 (Jan 14, 2026), with a median of $3.3319 per EA.
Are there cheaper alternatives to DOXYCYCLINE HYC DR 200 MG TAB?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DOXYCYCLINE HYC DR 200 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures DOXYCYCLINE HYC DR 200 MG TAB?
DOXYCYCLINE HYC DR 200 MG TAB (NDC 00591457560) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.