Doxycycline Hyclate
87 NDCs across 20 manufacturers|85 Generic,2 Brand
Doxycycline Hyclate is used to treat anthrax, campylobacter infections, cholera, granuloma inguinale, mycoplasma infections and plague, per the National Library of Medicine's MED-RT classification.
▸ More about this market▾ Less
The brand product was first FDA-approved before 1982, and the first generic was approved Jan 1, 1982. FDA's Orange Book lists 64 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $82 million on Doxycycline Hyclate across 6.7 million claims for 4.6 million beneficiaries.
Doxycycline Hyclate is available as 87 NDCs from 20 manufacturers (85 generic, 2 brand), with NADAC prices from $0.10 to $18.18 per EA — the most expensive product costs about 185× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
87
85G / 2B
Manufacturers
20
competing in market
Price Spread
$0.10 – $18.18
per EA
7d Activity
avg +4.4% WoW · of 87 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
Explore this market from other angles
Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.
Top supplier
Chartwell RX LLC manufacturer profile
Open the supplier page for the manufacturer with the strongest footprint in this market.
Lead class
Tetracycline-class Drug class view
See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.
Trend hub
Latest market trends
Move from this single molecule into the current cross-market mover and volatility view.
Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
20 manufacturers producing DOXYCYCLINE HYCLATE(2 pricing outliers)
Frequently Asked Questions
What is Doxycycline Hyclate used to treat?
Doxycycline Hyclate is used to treat anthrax, campylobacter infections, cholera, granuloma inguinale, mycoplasma infections and plague, per the National Library of Medicine's MED-RT classification.
When did Doxycycline Hyclate become available as a generic?
FDA approved the first generic Doxycycline Hyclate (ANDA) on Jan 1, 1982. The Orange Book currently lists 64 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Doxycycline Hyclate?
In 2024, Medicare Part D spent $82 million on Doxycycline Hyclate across 6.7 million claims for 4.6 million beneficiaries.
How many Doxycycline Hyclate products are on the market?
The Doxycycline Hyclate drug market contains 87 NDCs from 20 manufacturers — 85 generic and 2 brand products.
What is the price range for Doxycycline Hyclate?
NADAC reference prices for Doxycycline Hyclate range from $0.0984 to $18.1822 per EA — the most expensive product costs about 185× the cheapest.
Is generic Doxycycline Hyclate cheaper than brand?
The average generic NADAC for Doxycycline Hyclate is $0.8461 per EA, versus $18.1822 for brand-labeled products — brand versions average about 21× the generic price.
Which manufacturers make Doxycycline Hyclate?
20 manufacturers list Doxycycline Hyclate in NADAC. Ranked by number of NDCs, the largest are Chartwell RX LLC (13), Alembic Pharmaceuticals Inc. (10), Sun Pharmaceutical Industries Inc. (8), PuraCap Laboratories LLC (8), Viona Pharmaceuticals Inc. (5).
How has the price of Doxycycline Hyclate changed recently?
Over the past 7 days, 58 Doxycycline Hyclate NDCs rose and 11 fell, with a market-wide average change of +4.4%.