This NDC is on FDA's drug shortage list (posted Dec 20, 2023)
Product Information
FENTANYL 2,500 MCG/50 ML VIAL is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $1.7864 per ML under NDC 00641603001. Its NADAC has been published 576 times since Nov 28, 2013.
FDA first approved this application on Jul 11, 1984. Its Orange Book therapeutic-equivalence code is AP.
The Low Outlier badge above means this manufacturer's average price in the Fentanyl Citrate market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50 ug/mL
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00641603001
Classification
Generic
Dosage Form
INJECTION
Route
INTRAVENOUS
Effective Date
9/23/2026
Active Ingredients
FENTANYL CITRATEApproval Type
New Drug (NDA)
FDA Application
NDA019101FDA Approved
7/11/1984
TE Code
AP
On Market Since
7/11/1984
Pharmacological Classes
Price Statistics
The NADAC for FENTANYL 2,500 MCG/50 ML VIAL has been published 576 times since Nov 28, 2013, and over the history we have for it it has risen 249.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.7864 per ML |
|---|---|
| All-time high | $1.7864 (Sep 30, 2026) |
| All-time low | $0.3568 (Nov 19, 2014) |
| 52-week high | $1.7864 |
| 52-week low | $1.0131 |
| Median price | $0.6264 |
| Average price | $0.6651 |
| Largest weekly change | +82.4% (Jun 20, 2018) |
| Weeks tracked | 576 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 67% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Hikma Pharmaceuticals USA Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Fentanyl Citrate market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of FENTANYL 2,500 MCG/50 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for FENTANYL 2,500 MCG/50 ML VIAL, manufactured by Hikma Pharmaceuticals USA Inc., is $1.7864 per ML (NDC 00641603001), effective Sep 30, 2026.
How has the price of FENTANYL 2,500 MCG/50 ML VIAL changed over time?
Over the history we have for it, the NADAC for FENTANYL 2,500 MCG/50 ML VIAL has risen 249.4%. It has been tracked across 576 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for FENTANYL 2,500 MCG/50 ML VIAL?
Since Nov 28, 2013, the NADAC for FENTANYL 2,500 MCG/50 ML VIAL has ranged from a low of $0.3568 (Nov 19, 2014) to a high of $1.7864 (Sep 30, 2026), with a median of $0.6264 per ML.
Are there cheaper alternatives to FENTANYL 2,500 MCG/50 ML VIAL?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, FENTANYL 100 MCG/2 ML AMPUL, is $0.5981 per ML — about 67% below FENTANYL 2,500 MCG/50 ML VIAL.
Who manufactures FENTANYL 2,500 MCG/50 ML VIAL?
FENTANYL 2,500 MCG/50 ML VIAL (NDC 00641603001) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.
Is FENTANYL 2,500 MCG/50 ML VIAL in shortage?
Yes — NDC 00641603001 is currently listed in FDA's drug shortage database (posted Dec 20, 2023).