Product Information
ALPRAZOLAM 0.25 MG TABLET is a generic product labeled by Sandoz Inc., priced at $0.0239 per EA under NDC 00781106105. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Dec 29, 1995. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.25 mg/1
Manufacturer
Sandoz Inc.NDC
00781106105
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ALPRAZOLAMApproval Type
Generic (ANDA)
FDA Application
ANDA074112FDA Approved
12/29/1995
TE Code
AB
On Market Since
12/29/1995
Pharmacological Classes
Price Statistics
The NADAC for ALPRAZOLAM 0.25 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 12.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0239 per EA |
|---|---|
| All-time high | $0.0269 (Jul 12, 2023) |
| All-time low | $0.0176 (Jun 22, 2016) |
| 52-week high | $0.0250 |
| 52-week low | $0.0239 |
| Median price | $0.0216 |
| Average price | $0.0216 |
| Largest weekly change | +23.7% (Aug 21, 2024) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ALPRAZOLAM 0.25 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ALPRAZOLAM 0.25 MG TABLET, manufactured by Sandoz Inc., is $0.0239 per EA (NDC 00781106105), effective Aug 19, 2026.
How has the price of ALPRAZOLAM 0.25 MG TABLET changed over time?
Over the history we have for it, the NADAC for ALPRAZOLAM 0.25 MG TABLET has risen 12.3%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ALPRAZOLAM 0.25 MG TABLET?
Since Nov 28, 2013, the NADAC for ALPRAZOLAM 0.25 MG TABLET has ranged from a low of $0.0176 (Jun 22, 2016) to a high of $0.0269 (Jul 12, 2023), with a median of $0.0216 per EA.
Are there cheaper alternatives to ALPRAZOLAM 0.25 MG TABLET?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ALPRAZOLAM 0.25 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures ALPRAZOLAM 0.25 MG TABLET?
ALPRAZOLAM 0.25 MG TABLET (NDC 00781106105) is labeled by Sandoz Inc., and CMS classifies it as a generic product.