Product Information
ISOSORBIDE DINITRATE 5 MG TAB is a generic product labeled by Sandoz Inc., priced at $0.2064 per EA under NDC 00781163501. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Jan 7, 1988. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/1
Manufacturer
Sandoz Inc.NDC
00781163501
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ISOSORBIDE DINITRATEApproval Type
Generic (ANDA)
FDA Application
ANDA086221FDA Approved
1/7/1988
TE Code
AB
On Market Since
1/7/1988
Pharmacological Classes
Price Statistics
The NADAC for ISOSORBIDE DINITRATE 5 MG TAB has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 68.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2064 per EA |
|---|---|
| All-time high | $0.6995 (Mar 11, 2015) |
| All-time low | $0.1457 (Apr 17, 2024) |
| 52-week high | $0.2324 |
| 52-week low | $0.1938 |
| Median price | $0.3893 |
| Average price | $0.4100 |
| Largest weekly change | +54.4% (Jun 19, 2024) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ISOSORBIDE DINITRATE 5 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for ISOSORBIDE DINITRATE 5 MG TAB, manufactured by Sandoz Inc., is $0.2064 per EA (NDC 00781163501), effective Aug 19, 2026.
How has the price of ISOSORBIDE DINITRATE 5 MG TAB changed over time?
Over the history we have for it, the NADAC for ISOSORBIDE DINITRATE 5 MG TAB has declined 68.5%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ISOSORBIDE DINITRATE 5 MG TAB?
Since Nov 28, 2013, the NADAC for ISOSORBIDE DINITRATE 5 MG TAB has ranged from a low of $0.1457 (Apr 17, 2024) to a high of $0.6995 (Mar 11, 2015), with a median of $0.3893 per EA.
Are there cheaper alternatives to ISOSORBIDE DINITRATE 5 MG TAB?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ISOSORBIDE DINITRATE 5 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures ISOSORBIDE DINITRATE 5 MG TAB?
ISOSORBIDE DINITRATE 5 MG TAB (NDC 00781163501) is labeled by Sandoz Inc., and CMS classifies it as a generic product.