Product Information

OMEPRAZOLE DR 20 MG CAPSULE is a generic product labeled by Sandoz Inc., priced at $0.0286 per EA under NDC 00781286801. Its NADAC has been published 346 times since Oct 9, 2019.

FDA first approved this application on Jan 28, 2003. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

OMEPRAZOLE DR 20 MG CAPSULE

Omeprazole
$0.0286per EA

Strength

20 mg/1

Manufacturer

Sandoz Inc.

NDC

00781286801

Classification

Generic

Dosage Form

CAPSULE, DELAYED RELEASE

Route

ORAL

Effective Date

5/20/2026

Active Ingredients

OMEPRAZOLE

Approval Type

Generic (ANDA)

FDA Application

ANDA075757

FDA Approved

1/28/2003

TE Code

AB

On Market Since

7/1/2019

Pharmacological Classes

Cytochrome P450 2C19 Inhibitors
Proton Pump Inhibitor
Proton Pump Inhibitors

Price Statistics

The NADAC for OMEPRAZOLE DR 20 MG CAPSULE has been published 346 times since Oct 9, 2019, and over the history we have for it it has declined 29.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0286 per EA
All-time high$0.0446 (Mar 11, 2020)
All-time low$0.0265 (Nov 20, 2024)
52-week high$0.0321
52-week low$0.0285
Median price$0.0343
Average price$0.0356
Largest weekly change-25.0% (Apr 17, 2024)
Weeks tracked346
Tracking sinceOct 9, 2019

Price History

1W

N/A

1M

N/A

3M

N/A

6M

-2.1%

1Y

-11.0%

3Y

-10.6%

5Y

-24.1%

All

-29.1%

Last surveyed May 20, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 13 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of OMEPRAZOLE DR 20 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for OMEPRAZOLE DR 20 MG CAPSULE, manufactured by Sandoz Inc., is $0.0286 per EA (NDC 00781286801), effective May 20, 2026.

How has the price of OMEPRAZOLE DR 20 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for OMEPRAZOLE DR 20 MG CAPSULE has declined 29.1%. It has been tracked across 346 weekly CMS publications since Oct 9, 2019.

What are the highest and lowest recorded NADAC prices for OMEPRAZOLE DR 20 MG CAPSULE?

Since Oct 9, 2019, the NADAC for OMEPRAZOLE DR 20 MG CAPSULE has ranged from a low of $0.0265 (Nov 20, 2024) to a high of $0.0446 (Mar 11, 2020), with a median of $0.0343 per EA.

Are there cheaper alternatives to OMEPRAZOLE DR 20 MG CAPSULE?

Yes. 13 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, OMEPRAZOLE DR 20 MG CAPSULE, is $0.0277 per EA — about 3% below OMEPRAZOLE DR 20 MG CAPSULE.

Who manufactures OMEPRAZOLE DR 20 MG CAPSULE?

OMEPRAZOLE DR 20 MG CAPSULE (NDC 00781286801) is labeled by Sandoz Inc., and CMS classifies it as a generic product.