Product Information
METHYLPREDNISOLONE 400 MG/5 ML is a generic product labeled by Sandoz Inc., priced at $13.0533 per ML under NDC 00781351675. Its NADAC has been published 87 times since Sep 18, 2024.
FDA first approved this application on Jan 3, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
80 mg/mL
Manufacturer
Sandoz Inc.NDC
00781351675
Classification
Generic
Dosage Form
INJECTION, SUSPENSION
Route
INTRALESIONAL; INTRAMUSCULAR; INTRASYNOVIAL; SOFT TISSUE
Effective Date
5/21/2025
Active Ingredients
METHYLPREDNISOLONE ACETATEApproval Type
Generic (ANDA)
FDA Application
ANDA214870FDA Approved
1/3/2023
TE Code
AB
On Market Since
2/8/2023
Pharmacological Classes
Price Statistics
The NADAC for METHYLPREDNISOLONE 400 MG/5 ML has been published 87 times since Sep 18, 2024, and over the history we have for it it has declined 12.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $13.0533 per ML |
|---|---|
| All-time high | $14.9732 (Oct 16, 2024) |
| All-time low | $13.0533 (May 21, 2025) |
| 52-week high | $13.0533 |
| 52-week low | $13.0533 |
| Median price | $13.0533 |
| Average price | $13.4333 |
| Largest weekly change | -5.1% (Oct 23, 2024) |
| Weeks tracked | 87 |
| Tracking since | Sep 18, 2024 |
1W
N/A
1M
N/A
3M
N/A
6M
0.0%
1Y
0.0%
3Y
N/A
5Y
N/A
All
-12.8%
Last surveyed May 13, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the METHYLPREDNISOLONE ACETATE market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METHYLPREDNISOLONE 400 MG/5 ML?
The current National Average Drug Acquisition Cost (NADAC) for METHYLPREDNISOLONE 400 MG/5 ML, manufactured by Sandoz Inc., is $13.0533 per ML (NDC 00781351675), effective May 13, 2026.
How has the price of METHYLPREDNISOLONE 400 MG/5 ML changed over time?
Over the history we have for it, the NADAC for METHYLPREDNISOLONE 400 MG/5 ML has declined 12.8%. It has been tracked across 87 weekly CMS publications since Sep 18, 2024.
What are the highest and lowest recorded NADAC prices for METHYLPREDNISOLONE 400 MG/5 ML?
Since Sep 18, 2024, the NADAC for METHYLPREDNISOLONE 400 MG/5 ML has ranged from a low of $13.0533 (May 21, 2025) to a high of $14.9732 (Oct 16, 2024), with a median of $13.0533 per ML.
Are there cheaper alternatives to METHYLPREDNISOLONE 400 MG/5 ML?
No other NADAC-published product currently shares the active ingredient and strength of METHYLPREDNISOLONE 400 MG/5 ML in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures METHYLPREDNISOLONE 400 MG/5 ML?
METHYLPREDNISOLONE 400 MG/5 ML (NDC 00781351675) is labeled by Sandoz Inc., and CMS classifies it as a generic product.