Product Information
DIFLUPREDNATE 0.05% EYE DROP is a generic product labeled by Upsher-Smith Laboratories LLC, priced at $7.0479 per ML under NDC 00832605405. Its NADAC has been published 30 times since Dec 3, 2025.
Strength
.5 mg/mL
Manufacturer
Upsher-Smith Laboratories LLCNDC
00832605405
Classification
Generic
Dosage Form
EMULSION
Route
OPHTHALMIC
Last Updated
6/17/2026
Active Ingredients
DIFLUPREDNATEApproval Type
Generic (ANDA)
FDA Application
ANDA218191On Market Since
2/21/2025
Price Statistics
The NADAC for DIFLUPREDNATE 0.05% EYE DROP has been published 30 times since Dec 3, 2025, and over the history we have for it it has declined 29.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.0479 per ML |
|---|---|
| All-time high | $10.4599 (Feb 11, 2026) |
| All-time low | $7.0479 (Jun 17, 2026) |
| 52-week high | $10.4599 |
| 52-week low | $7.0479 |
| Median price | $9.6839 |
| Average price | $9.3748 |
| Largest weekly change | -13.1% (Jun 17, 2026) |
| Weeks tracked | 30 |
| Tracking since | Dec 3, 2025 |
Generic Alternatives
The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of DIFLUPREDNATE 0.05% EYE DROP?
The current National Average Drug Acquisition Cost (NADAC) for DIFLUPREDNATE 0.05% EYE DROP, manufactured by Upsher-Smith Laboratories LLC, is $7.0479 per ML (NDC 00832605405), effective Jun 24, 2026.
How has the price of DIFLUPREDNATE 0.05% EYE DROP changed over time?
Over the history we have for it, the NADAC for DIFLUPREDNATE 0.05% EYE DROP has declined 29.8%. It has been tracked across 30 weekly CMS publications since Dec 3, 2025.
What are the highest and lowest recorded NADAC prices for DIFLUPREDNATE 0.05% EYE DROP?
Since Dec 3, 2025, the NADAC for DIFLUPREDNATE 0.05% EYE DROP has ranged from a low of $7.0479 (Jun 17, 2026) to a high of $10.4599 (Feb 11, 2026), with a median of $9.6839 per ML.
Are there cheaper alternatives to DIFLUPREDNATE 0.05% EYE DROP?
2 NADAC-published products share the same active ingredient, strength, and dosage form as DIFLUPREDNATE 0.05% EYE DROP, but none are currently priced below it.
Who manufactures DIFLUPREDNATE 0.05% EYE DROP?
DIFLUPREDNATE 0.05% EYE DROP (NDC 00832605405) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a generic product.
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