Product Information
MESALAMINE ER 0.375 GRAM CAP is a generic product labeled by Upsher-Smith Laboratories LLC, priced at $0.4865 per EA under NDC 00832605612. Its NADAC has been published 152 times since Sep 27, 2023.
FDA first approved this application on Jun 6, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.375 g/1
Manufacturer
Upsher-Smith Laboratories LLCNDC
00832605612
Classification
Generic
Dosage Form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
MESALAMINEApproval Type
Generic (ANDA)
FDA Application
ANDA217533FDA Approved
6/6/2023
TE Code
AB
On Market Since
6/6/2023
Pharmacological Classes
Price Statistics
The NADAC for MESALAMINE ER 0.375 GRAM CAP has been published 152 times since Sep 27, 2023, and over the history we have for it it has declined 46.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4865 per EA |
|---|---|
| All-time high | $0.9198 (Feb 14, 2024) |
| All-time low | $0.4196 (Feb 18, 2026) |
| 52-week high | $0.4979 |
| 52-week low | $0.4196 |
| Median price | $0.4926 |
| Average price | $0.5585 |
| Largest weekly change | -38.7% (Jul 17, 2024) |
| Weeks tracked | 152 |
| Tracking since | Sep 27, 2023 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of MESALAMINE ER 0.375 GRAM CAP?
The current National Average Drug Acquisition Cost (NADAC) for MESALAMINE ER 0.375 GRAM CAP, manufactured by Upsher-Smith Laboratories LLC, is $0.4865 per EA (NDC 00832605612), effective Aug 19, 2026.
How has the price of MESALAMINE ER 0.375 GRAM CAP changed over time?
Over the history we have for it, the NADAC for MESALAMINE ER 0.375 GRAM CAP has declined 46.8%. It has been tracked across 152 weekly CMS publications since Sep 27, 2023.
What are the highest and lowest recorded NADAC prices for MESALAMINE ER 0.375 GRAM CAP?
Since Sep 27, 2023, the NADAC for MESALAMINE ER 0.375 GRAM CAP has ranged from a low of $0.4196 (Feb 18, 2026) to a high of $0.9198 (Feb 14, 2024), with a median of $0.4926 per EA.
Are there cheaper alternatives to MESALAMINE ER 0.375 GRAM CAP?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as MESALAMINE ER 0.375 GRAM CAP in a comparable dosage form, but none are currently priced below it.
Who manufactures MESALAMINE ER 0.375 GRAM CAP?
MESALAMINE ER 0.375 GRAM CAP (NDC 00832605612) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a generic product.