Product Information
TRI-BUFFERED ASPIRIN 325 MG TB is a generic product labeled by Major Pharmaceuticals, priced at $0.0207 per EA under NDC 00904201559. Its NADAC has been published 657 times since Nov 28, 2013.
Strength
325 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904201559
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
ASPIRINApproval Type
OTC MONOGRAPH DRUG
FDA Application
M013On Market Since
3/30/1990
Pharmacological Classes
Price Statistics
The NADAC for TRI-BUFFERED ASPIRIN 325 MG TB has been published 657 times since Nov 28, 2013, and over the history we have for it it has risen 13.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0207 per EA |
|---|---|
| All-time high | $0.0225 (Mar 14, 2018) |
| All-time low | $0.0163 (Feb 19, 2014) |
| 52-week high | $0.0207 |
| 52-week low | $0.0198 |
| Median price | $0.0189 |
| Average price | $0.0190 |
| Largest weekly change | +17.9% (Feb 21, 2018) |
| Weeks tracked | 657 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 42% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of TRI-BUFFERED ASPIRIN 325 MG TB?
The current National Average Drug Acquisition Cost (NADAC) for TRI-BUFFERED ASPIRIN 325 MG TB, manufactured by Major Pharmaceuticals, is $0.0207 per EA (NDC 00904201559), effective Jun 24, 2026.
How has the price of TRI-BUFFERED ASPIRIN 325 MG TB changed over time?
Over the history we have for it, the NADAC for TRI-BUFFERED ASPIRIN 325 MG TB has risen 13.1%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for TRI-BUFFERED ASPIRIN 325 MG TB?
Since Nov 28, 2013, the NADAC for TRI-BUFFERED ASPIRIN 325 MG TB has ranged from a low of $0.0163 (Feb 19, 2014) to a high of $0.0225 (Mar 14, 2018), with a median of $0.0189 per EA.
Are there cheaper alternatives to TRI-BUFFERED ASPIRIN 325 MG TB?
Yes. 6 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, QC ASPIRIN 325 MG TABLET, is $0.0121 per EA — about 42% below TRI-BUFFERED ASPIRIN 325 MG TB.
Who manufactures TRI-BUFFERED ASPIRIN 325 MG TB?
TRI-BUFFERED ASPIRIN 325 MG TB (NDC 00904201559) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.
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