Product Information
CALAMINE LOTION is a generic product labeled by Major Pharmaceuticals, priced at $0.0110 per ML under NDC 00904253321. Its NADAC has been published 626 times since Aug 27, 2014.
Strength
80; 80 mg/mL; mg/mL
Manufacturer
Major PharmaceuticalsNDC
00904253321
Classification
Generic
Dosage Form
LOTION
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
FERRIC OXIDE RED; ZINC OXIDEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M016On Market Since
1/7/2013
Price Statistics
The NADAC for CALAMINE LOTION has been published 626 times since Aug 27, 2014, and over the history we have for it it has risen 27.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0110 per ML |
|---|---|
| All-time high | $0.0111 (Nov 12, 2025) |
| All-time low | $0.0077 (Nov 17, 2021) |
| 52-week high | $0.0111 |
| 52-week low | $0.0100 |
| Median price | $0.0086 |
| Average price | $0.0090 |
| Largest weekly change | +12.1% (Mar 20, 2024) |
| Weeks tracked | 626 |
| Tracking since | Aug 27, 2014 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 20% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CALAMINE LOTION?
The current National Average Drug Acquisition Cost (NADAC) for CALAMINE LOTION, manufactured by Major Pharmaceuticals, is $0.0110 per ML (NDC 00904253321), effective Aug 19, 2026.
How has the price of CALAMINE LOTION changed over time?
Over the history we have for it, the NADAC for CALAMINE LOTION has risen 27.3%. It has been tracked across 626 weekly CMS publications since Aug 27, 2014.
What are the highest and lowest recorded NADAC prices for CALAMINE LOTION?
Since Aug 27, 2014, the NADAC for CALAMINE LOTION has ranged from a low of $0.0077 (Nov 17, 2021) to a high of $0.0111 (Nov 12, 2025), with a median of $0.0086 per ML.
Are there cheaper alternatives to CALAMINE LOTION?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CALAMINE LOTION, is $0.0089 per ML — about 20% below CALAMINE LOTION.
Who manufactures CALAMINE LOTION?
CALAMINE LOTION (NDC 00904253321) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.