Product Information

MEMANTINE HCL ER 28 MG CAPSULE is a generic product labeled by Major Pharmaceuticals, priced at $0.4884 per EA under NDC 00904673561. Its NADAC has been published 380 times since Feb 20, 2019.

FDA first approved this application on Sep 28, 2016. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

MEMANTINE HCL ER 28 MG CAPSULE

memantine hydrochloride
$0.4884per EA

Strength

28 mg/1

NDC

00904673561

Classification

Generic

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

5/20/2026

Active Ingredients

MEMANTINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA206028

FDA Approved

9/28/2016

TE Code

AB

On Market Since

2/20/2018

Pharmacological Classes

Price Statistics

The NADAC for MEMANTINE HCL ER 28 MG CAPSULE has been published 380 times since Feb 20, 2019, and over the history we have for it it has declined 86.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.4884 per EA
All-time high$3.6704 (May 15, 2019)
All-time low$0.4491 (Jul 17, 2024)
52-week high$0.5628
52-week low$0.4679
Median price$0.7790
Average price$1.2816
Largest weekly change-32.6% (Jul 17, 2024)
Weeks tracked380
Tracking sinceFeb 20, 2019

Price History

1W

N/A

1M

N/A

3M

0.0%

6M

+4.4%

1Y

-13.2%

3Y

-28.4%

5Y

-68.4%

All

-86.4%

Last surveyed May 27, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 22% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of MEMANTINE HCL ER 28 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for MEMANTINE HCL ER 28 MG CAPSULE, manufactured by Major Pharmaceuticals, is $0.4884 per EA (NDC 00904673561), effective May 27, 2026.

How has the price of MEMANTINE HCL ER 28 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for MEMANTINE HCL ER 28 MG CAPSULE has declined 86.4%. It has been tracked across 380 weekly CMS publications since Feb 20, 2019.

What are the highest and lowest recorded NADAC prices for MEMANTINE HCL ER 28 MG CAPSULE?

Since Feb 20, 2019, the NADAC for MEMANTINE HCL ER 28 MG CAPSULE has ranged from a low of $0.4491 (Jul 17, 2024) to a high of $3.6704 (May 15, 2019), with a median of $0.7790 per EA.

Are there cheaper alternatives to MEMANTINE HCL ER 28 MG CAPSULE?

Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, MEMANTINE HCL ER 28 MG CAPSULE, is $0.3793 per EA — about 22% below MEMANTINE HCL ER 28 MG CAPSULE.

Who manufactures MEMANTINE HCL ER 28 MG CAPSULE?

MEMANTINE HCL ER 28 MG CAPSULE (NDC 00904673561) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.