Product Information
MEMANTINE HCL ER 28 MG CAPSULE is a generic product labeled by Major Pharmaceuticals, priced at $0.4884 per EA under NDC 00904673561. Its NADAC has been published 380 times since Feb 20, 2019.
FDA first approved this application on Sep 28, 2016. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
28 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904673561
Classification
Generic
Dosage Form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Effective Date
5/20/2026
Active Ingredients
MEMANTINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA206028FDA Approved
9/28/2016
TE Code
AB
On Market Since
2/20/2018
Pharmacological Classes
Price Statistics
The NADAC for MEMANTINE HCL ER 28 MG CAPSULE has been published 380 times since Feb 20, 2019, and over the history we have for it it has declined 86.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4884 per EA |
|---|---|
| All-time high | $3.6704 (May 15, 2019) |
| All-time low | $0.4491 (Jul 17, 2024) |
| 52-week high | $0.5387 |
| 52-week low | $0.4679 |
| Median price | $0.7790 |
| Average price | $1.2816 |
| Largest weekly change | -32.6% (Jul 17, 2024) |
| Weeks tracked | 380 |
| Tracking since | Feb 20, 2019 |
1W
N/A
1M
N/A
3M
N/A
6M
-1.1%
1Y
-6.9%
3Y
-24.3%
5Y
-66.0%
All
-86.4%
Last surveyed May 27, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 30% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Major Pharmaceuticals manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
memantine hydrochloride market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
N-methyl-D-aspartate Receptor Antagonist class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of MEMANTINE HCL ER 28 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for MEMANTINE HCL ER 28 MG CAPSULE, manufactured by Major Pharmaceuticals, is $0.4884 per EA (NDC 00904673561), effective May 27, 2026.
How has the price of MEMANTINE HCL ER 28 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for MEMANTINE HCL ER 28 MG CAPSULE has declined 86.4%. It has been tracked across 380 weekly CMS publications since Feb 20, 2019.
What are the highest and lowest recorded NADAC prices for MEMANTINE HCL ER 28 MG CAPSULE?
Since Feb 20, 2019, the NADAC for MEMANTINE HCL ER 28 MG CAPSULE has ranged from a low of $0.4491 (Jul 17, 2024) to a high of $3.6704 (May 15, 2019), with a median of $0.7790 per EA.
Are there cheaper alternatives to MEMANTINE HCL ER 28 MG CAPSULE?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, MEMANTINE HCL ER 28 MG CAPSULE, is $0.3422 per EA — about 30% below MEMANTINE HCL ER 28 MG CAPSULE.
Who manufactures MEMANTINE HCL ER 28 MG CAPSULE?
MEMANTINE HCL ER 28 MG CAPSULE (NDC 00904673561) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.