Product Information
SERTRALINE HCL 50 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.0345 per EA under NDC 00904692561. Its NADAC has been published 292 times since Jan 20, 2021.
FDA first approved this application on Feb 6, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904692561
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
SERTRALINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA077670FDA Approved
2/6/2007
TE Code
AB
On Market Since
2/6/2007
Pharmacological Classes
Price Statistics
The NADAC for SERTRALINE HCL 50 MG TABLET has been published 292 times since Jan 20, 2021, and over the history we have for it it has declined 37.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0345 per EA |
|---|---|
| All-time high | $0.0548 (Mar 10, 2021) |
| All-time low | $0.0292 (Nov 20, 2024) |
| 52-week high | $0.0388 |
| 52-week low | $0.0343 |
| Median price | $0.0407 |
| Average price | $0.0408 |
| Largest weekly change | -26.1% (Nov 20, 2024) |
| Weeks tracked | 292 |
| Tracking since | Jan 20, 2021 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SERTRALINE HCL 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for SERTRALINE HCL 50 MG TABLET, manufactured by Major Pharmaceuticals, is $0.0345 per EA (NDC 00904692561), effective Aug 19, 2026.
How has the price of SERTRALINE HCL 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for SERTRALINE HCL 50 MG TABLET has declined 37.0%. It has been tracked across 292 weekly CMS publications since Jan 20, 2021.
What are the highest and lowest recorded NADAC prices for SERTRALINE HCL 50 MG TABLET?
Since Jan 20, 2021, the NADAC for SERTRALINE HCL 50 MG TABLET has ranged from a low of $0.0292 (Nov 20, 2024) to a high of $0.0548 (Mar 10, 2021), with a median of $0.0407 per EA.
Are there cheaper alternatives to SERTRALINE HCL 50 MG TABLET?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as SERTRALINE HCL 50 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures SERTRALINE HCL 50 MG TABLET?
SERTRALINE HCL 50 MG TABLET (NDC 00904692561) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.