Product Information
SERTRALINE HCL 50 MG TABLET is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.0345 per EA under NDC 68180098604. Its NADAC has been published 43 times since Oct 29, 2025.
FDA first approved this application on Feb 6, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Lupin Pharmaceuticals Inc.NDC
68180098604
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
SERTRALINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA077670FDA Approved
2/6/2007
TE Code
AB
On Market Since
8/6/2025
Pharmacological Classes
Price Statistics
The NADAC for SERTRALINE HCL 50 MG TABLET has been published 43 times since Oct 29, 2025, and over the history we have for it it has declined 3.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0345 per EA |
|---|---|
| All-time high | $0.0388 (Feb 11, 2026) |
| All-time low | $0.0343 (Jun 17, 2026) |
| 52-week high | $0.0388 |
| 52-week low | $0.0343 |
| Median price | $0.0353 |
| Average price | $0.0360 |
| Largest weekly change | -6.6% (Feb 18, 2026) |
| Weeks tracked | 43 |
| Tracking since | Oct 29, 2025 |
Generic Alternatives
The matcher finds 8 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SERTRALINE HCL 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for SERTRALINE HCL 50 MG TABLET, manufactured by Lupin Pharmaceuticals Inc., is $0.0345 per EA (NDC 68180098604), effective Aug 19, 2026.
How has the price of SERTRALINE HCL 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for SERTRALINE HCL 50 MG TABLET has declined 3.6%. It has been tracked across 43 weekly CMS publications since Oct 29, 2025.
What are the highest and lowest recorded NADAC prices for SERTRALINE HCL 50 MG TABLET?
Since Oct 29, 2025, the NADAC for SERTRALINE HCL 50 MG TABLET has ranged from a low of $0.0343 (Jun 17, 2026) to a high of $0.0388 (Feb 11, 2026), with a median of $0.0353 per EA.
Are there cheaper alternatives to SERTRALINE HCL 50 MG TABLET?
8 manufacturers publish a NADAC-priced product with the same active ingredient and strength as SERTRALINE HCL 50 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures SERTRALINE HCL 50 MG TABLET?
SERTRALINE HCL 50 MG TABLET (NDC 68180098604) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.