Product Information
CAPTOPRIL 12.5 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.2295 per EA under NDC 00904710561. Its NADAC has been published 262 times since Aug 18, 2021.
FDA first approved this application on Dec 13, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The Low Outlier badge above means this manufacturer's average price in the Captopril market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
12.5 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904710561
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
CAPTOPRILApproval Type
Generic (ANDA)
FDA Application
ANDA212809FDA Approved
12/13/2019
TE Code
AB
On Market Since
12/13/2019
Pharmacological Classes
Price Statistics
The NADAC for CAPTOPRIL 12.5 MG TABLET has been published 262 times since Aug 18, 2021, and over the history we have for it it has declined 45.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2295 per EA |
|---|---|
| All-time high | $0.6898 (Apr 10, 2024) |
| All-time low | $0.1816 (Mar 19, 2025) |
| 52-week high | $0.4059 |
| 52-week low | $0.2295 |
| Median price | $0.4034 |
| Average price | $0.4028 |
| Largest weekly change | +125.8% (Aug 17, 2022) |
| Weeks tracked | 262 |
| Tracking since | Aug 18, 2021 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CAPTOPRIL 12.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for CAPTOPRIL 12.5 MG TABLET, manufactured by Major Pharmaceuticals, is $0.2295 per EA (NDC 00904710561), effective Aug 19, 2026.
How has the price of CAPTOPRIL 12.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for CAPTOPRIL 12.5 MG TABLET has declined 45.2%. It has been tracked across 262 weekly CMS publications since Aug 18, 2021.
What are the highest and lowest recorded NADAC prices for CAPTOPRIL 12.5 MG TABLET?
Since Aug 18, 2021, the NADAC for CAPTOPRIL 12.5 MG TABLET has ranged from a low of $0.1816 (Mar 19, 2025) to a high of $0.6898 (Apr 10, 2024), with a median of $0.4034 per EA.
Are there cheaper alternatives to CAPTOPRIL 12.5 MG TABLET?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CAPTOPRIL 12.5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures CAPTOPRIL 12.5 MG TABLET?
CAPTOPRIL 12.5 MG TABLET (NDC 00904710561) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.