Product Information

CAPTOPRIL 25 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.1743 per EA under NDC 00904710661. Its NADAC has been published 262 times since Aug 18, 2021.

FDA first approved this application on Dec 13, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The Low Outlier badge above means this manufacturer's average price in the Captopril market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

CAPTOPRIL 25 MG TABLET

Captopril
$0.1743per EA
Low Outlier

Strength

25 mg/1

NDC

00904710661

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

CAPTOPRIL

Approval Type

Generic (ANDA)

FDA Application

ANDA212809

FDA Approved

12/13/2019

TE Code

AB

On Market Since

12/13/2019

Pharmacological Classes

Angiotensin Converting Enzyme Inhibitor
Angiotensin-converting Enzyme Inhibitors

Price Statistics

The NADAC for CAPTOPRIL 25 MG TABLET has been published 262 times since Aug 18, 2021, and over the history we have for it it has declined 66.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1743 per EA
All-time high$0.6800 (Dec 15, 2021)
All-time low$0.1060 (Aug 20, 2025)
52-week high$0.1826
52-week low$0.1060
Median price$0.3250
Average price$0.3396
Largest weekly change+109.0% (May 17, 2023)
Weeks tracked262
Tracking sinceAug 18, 2021

Price History

1W

+8.3%

1M

+8.3%

3M

+38.2%

6M

+19.0%

1Y

+64.5%

3Y

-59.2%

5Y

-66.2%

All

-66.2%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CAPTOPRIL 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for CAPTOPRIL 25 MG TABLET, manufactured by Major Pharmaceuticals, is $0.1743 per EA (NDC 00904710661), effective Aug 19, 2026.

How has the price of CAPTOPRIL 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for CAPTOPRIL 25 MG TABLET has declined 66.2%. It has been tracked across 262 weekly CMS publications since Aug 18, 2021.

What are the highest and lowest recorded NADAC prices for CAPTOPRIL 25 MG TABLET?

Since Aug 18, 2021, the NADAC for CAPTOPRIL 25 MG TABLET has ranged from a low of $0.1060 (Aug 20, 2025) to a high of $0.6800 (Dec 15, 2021), with a median of $0.3250 per EA.

Are there cheaper alternatives to CAPTOPRIL 25 MG TABLET?

Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CAPTOPRIL 25 MG TABLET, is $0.1732 per EA — about 1% below CAPTOPRIL 25 MG TABLET.

Who manufactures CAPTOPRIL 25 MG TABLET?

CAPTOPRIL 25 MG TABLET (NDC 00904710661) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.