Product Information
CAPTOPRIL 25 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.1728 per EA under NDC 00904710661. Its NADAC has been published 268 times since Aug 18, 2021.
FDA first approved this application on Dec 13, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The Low Outlier badge above means this manufacturer's average price in the Captopril market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
25 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904710661
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
CAPTOPRILApproval Type
Generic (ANDA)
FDA Application
ANDA212809FDA Approved
12/13/2019
TE Code
AB
On Market Since
12/13/2019
Pharmacological Classes
Price Statistics
The NADAC for CAPTOPRIL 25 MG TABLET has been published 268 times since Aug 18, 2021, and over the history we have for it it has declined 66.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1728 per EA |
|---|---|
| All-time high | $0.6800 (Dec 15, 2021) |
| All-time low | $0.1060 (Aug 20, 2025) |
| 52-week high | $0.1826 |
| 52-week low | $0.1178 |
| Median price | $0.3210 |
| Average price | $0.3359 |
| Largest weekly change | +109.0% (May 17, 2023) |
| Weeks tracked | 268 |
| Tracking since | Aug 18, 2021 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Major Pharmaceuticals manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Captopril market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Angiotensin Converting Enzyme Inhibitor class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CAPTOPRIL 25 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for CAPTOPRIL 25 MG TABLET, manufactured by Major Pharmaceuticals, is $0.1728 per EA (NDC 00904710661), effective Sep 30, 2026.
How has the price of CAPTOPRIL 25 MG TABLET changed over time?
Over the history we have for it, the NADAC for CAPTOPRIL 25 MG TABLET has declined 66.5%. It has been tracked across 268 weekly CMS publications since Aug 18, 2021.
What are the highest and lowest recorded NADAC prices for CAPTOPRIL 25 MG TABLET?
Since Aug 18, 2021, the NADAC for CAPTOPRIL 25 MG TABLET has ranged from a low of $0.1060 (Aug 20, 2025) to a high of $0.6800 (Dec 15, 2021), with a median of $0.3210 per EA.
Are there cheaper alternatives to CAPTOPRIL 25 MG TABLET?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CAPTOPRIL 25 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures CAPTOPRIL 25 MG TABLET?
CAPTOPRIL 25 MG TABLET (NDC 00904710661) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.