Product Information
MEGESTROL 40 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.2408 per EA under NDC 00904723661. Its NADAC has been published 198 times since Dec 21, 2022.
FDA first approved this application on Aug 8, 1988. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
40 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904723661
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
MEGESTROL ACETATEApproval Type
Generic (ANDA)
FDA Application
ANDA072423FDA Approved
8/8/1988
TE Code
AB
On Market Since
4/4/2022
Pharmacological Classes
Price Statistics
The NADAC for MEGESTROL 40 MG TABLET has been published 198 times since Dec 21, 2022, and over the history we have for it it has risen 18.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2408 per EA |
|---|---|
| All-time high | $0.2465 (Sep 16, 2026) |
| All-time low | $0.1792 (Apr 17, 2024) |
| 52-week high | $0.2465 |
| 52-week low | $0.2092 |
| Median price | $0.2067 |
| Average price | $0.2096 |
| Largest weekly change | +14.2% (Oct 18, 2023) |
| Weeks tracked | 198 |
| Tracking since | Dec 21, 2022 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Major Pharmaceuticals manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Megestrol Acetate market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Progestin class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of MEGESTROL 40 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for MEGESTROL 40 MG TABLET, manufactured by Major Pharmaceuticals, is $0.2408 per EA (NDC 00904723661), effective Sep 30, 2026.
How has the price of MEGESTROL 40 MG TABLET changed over time?
Over the history we have for it, the NADAC for MEGESTROL 40 MG TABLET has risen 18.1%. It has been tracked across 198 weekly CMS publications since Dec 21, 2022.
What are the highest and lowest recorded NADAC prices for MEGESTROL 40 MG TABLET?
Since Dec 21, 2022, the NADAC for MEGESTROL 40 MG TABLET has ranged from a low of $0.1792 (Apr 17, 2024) to a high of $0.2465 (Sep 16, 2026), with a median of $0.2067 per EA.
Are there cheaper alternatives to MEGESTROL 40 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as MEGESTROL 40 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures MEGESTROL 40 MG TABLET?
MEGESTROL 40 MG TABLET (NDC 00904723661) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.